Clinical Bioinformatics Specialist

National Institutes of Health • Montgomery County, MD

23d

About The Position

The Clinical Bioinformatics Specialist works in the Center for Biomedical Informatics and Information Technology (CBIIT), National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (HHS). The role provides technical direction and scientific oversight for the full software development lifecycle of Semantic Infrastructure applications that support the cancer Data Standards Registry and Repository (caDSR) and Enterprise Vocabulary Services (EVS). The specialist serves as the expert on the Semantic Infrastructure application portfolio, including caDSR II, EVS Explore, MEME, and related ontology, terminology, and data-element platforms. The position oversees the design, development, and operationalization of infrastructure supporting biomedical data models and knowledgebases; plans and prioritizes software development, modernization, and sustainment; and oversees AI and machine learning tools for creation, curation, mapping, quality assurance, and lifecycle management of semantic resources.

This position requires a bachelor's or graduate/higher-level degree in a major study related to the medical field, health sciences, or allied sciences appropriate to the work, plus at least one year of qualifying specialized experience equivalent to the GS-13 level in Federal service. The selected candidate must meet U.S. citizenship or U.S. national requirements and applicable qualification, documentation, and background-investigation requirements. The position is designated non-emergency/teleworker; the employee must be available to telework or request leave in the event of a closure. Alternative Work Schedules and Maxiflex Schedules may be offered at the supervisor's discretion.

Requirements

• U.S. citizenship or proof of U.S. national status by the announcement closing date.
• A bachelor's or graduate/higher-level degree in a major study in an academic field related to the medical field, health sciences, or allied sciences appropriate to the work; the degree must be from an educational program accredited by a body recognized by the U.S. Department of Education when the degree was obtained.
• At least one year of qualifying specialized experience equivalent to at least the GS-13 level in Federal service, gained in the public or private sector.
• Specialized experience providing technical guidance to developers and data scientists on semantic resources, knowledge graphs, and metadata infrastructure for AI and analytics.
• Specialized experience configuring semantic infrastructure to expose biomedical content for AI, including LLM, RAG, and ML pipelines.
• Specialized experience designing semantic infrastructure for biomedical knowledgebases, including RDF triple stores and labeled property graphs.
• Specialized experience providing technical direction for software development and sustainment using Agile, DevSecOps, and cloud-native processes.
• Specialized experience applying health and clinical data standards for interoperability across biomedical platforms.
• Specialized experience applying ontology and metadata standards for FAIR-aligned workflows.
• Submit transcripts or a list of courses, including titles, credit hours completed, and grades; official transcripts are required from selectees before an official offer.
• Meet all qualification requirements by the announcement closing date.
• Successfully complete applicable background investigation, qualification verification, onboarding forms, required-document submission, and other job-related requirements.
• Males born after December 31, 1959 must be registered with the Selective Service.
• Be able to perform the essential duties, with or without reasonable accommodation.
• A one- or two-year trial/probationary period may be required, depending on appointment.

Responsibilities

• Provide expert technical direction and scientific oversight for the full software development lifecycle of Semantic Infrastructure applications supporting caDSR and EVS.
• Serve as the expert on the Semantic Infrastructure application portfolio, including caDSR II, EVS Explore, MEME, and related ontology, terminology, and data-element platforms.
• Oversee the design, development, and operationalization of Semantic Infrastructure application infrastructure supporting biomedical data models and knowledgebases.
• Oversee planning, prioritization, and execution of software development, modernization, and sustainment activities for the Semantic Infrastructure application portfolio.
• Oversee development, deployment, and maintenance of AI and machine learning tools for creation, curation, mapping, quality assurance, and lifecycle management of semantic resources.

Benefits

• Federal employee benefits package, with access to benefits for employees and their families; specific eligibility depends on position type.
• Alternative Work Schedules and Maxiflex Schedules may be available at the supervisor's discretion.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior