Cell Manufacturing Assistant, Biotherapeutics Core
About The Position
The Biotherapeutics Core Facility (BTCF) at Memorial Sloan Kettering Cancer Center (MSK) develops, validates, and implements procedures critical to gene transfer-related clinical research. This includes genetic engineering and ex vivo transduction of patient cells, cell line development, vector production, R&D and process development work relating to vector production and transduction of patient cells, and analysis of gene transfer efficiency and transgene expression in patient cells. BTCF enables the translation of innovative research concepts into clinically relevant studies, supporting the development of new strategies for understanding and applying gene-based therapies. We are seeking a meticulous and proactive individual with excellent organizational skills and strong attention to detail as a Cell Manufacturing Assistant to assist in these areas under general supervision.
Requirements
- BA/BS with five (5) years related experience or MA/MS with three (3) years related experience
- Experience with molecular and/or cellular biology techniques
- Knowledge of basic computer applications and ability to use MS Office software
Nice To Haves
- Previous experience in cGMP or clinically regulated environment
- Knowledge of biotechnologies
Responsibilities
- Participate in the cGMP Production of large-scale clinical-grade products such as, NK, TCR, and T cell products
- Assist in the production/development and quality control of ancillary cells, such as master cell banks
- Analyze gene expressions in cell lines, primary cell lines, and research samples using FACS, PCR, qPCR, etc
- Participate in process validation and tech transfer activities
- Participate in planning and discussion of laboratory projects with team leaders and managers
- Operate and maintain complex laboratory equipment such as FACS machine, qPCR machine, cell washers, and bioreactors
- Complete all documentation per GDP and cGMP regulation per BTCF’s SOPs and maintaining detailed experimental records
- Proactively participate in data analysis, data summary, data evaluation, and maintenance of corresponding databases in an accurate and timely fashion
- Development, writing and updating of SOPs and material lists
- General lab upkeep and organization
Benefits
- Compensation Philosophy
- Benefits
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
