Cell Line Development Scientist

Demeetra Agbio Inc.Lexington, KY
Onsite

About The Position

Demeetra is seeking a highly motivated Cell Line Development Scientist to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. This role is designed for someone who is eager, hands-on, detail-driven, and experienced enough to contribute with minimal onboard training. The successful candidate must be driven by a culture of excellence and ready for intense, high-expectation, hands-on CLD workflows, bringing industry experience that enables them to contribute at a high level from day one, ideally in a CRO or CDMO setting. You will be a key contributor in developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s cutting-edge gene editing platforms. This position is ideal for recent graduates (MS or PhD) and are eager to take ownership of experimental design, workflow execution, and timeline-driven deliverables.

Requirements

  • MS or PhD in biology, biochemistry, biotechnology, or related field required
  • Demonstrated proficiency in: Molecular biology and vector construction
  • Suspension CHO cell culture
  • Transfection & selection workflows
  • Shake flask, spin tube, and deep-well plate fed-batch processes
  • Single-cell cloning
  • Titer determination and standard downstream quality assessments
  • Analytical techniques such as HPLC, LC/MS, and/or CE.
  • Ability to thrive in a high-expectation, fast-moving environment
  • Strong communication, organization, and documentation skills

Nice To Haves

  • Analytical experience (HPLC) is a plus.

Responsibilities

  • Execute CHO cell culture processes across shake flasks and spin tube fed-batch formats
  • Perform transfection, selection, single-cell cloning, and clone characterization workflows
  • Support upstream development with high attention to process consistency and data integrity
  • Vector design and molecular biology
  • Run titer and basic downstream quality assays to assess productivity and cell line performance, analytical experience (HPLC) is a plus.
  • Collaborate cross-functionally to implement advanced gene editing technologies in CLD
  • Contribute to workflow design, documentation, and continuous process improvement
  • Maintain a culture of excellence, accountability, and meeting or exceeding timelines
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