ProFound Therapeutics: Cardiovascular, Metabolic & Neuroscience Co-Op
About The Position
This position is open exclusively to current Northeastern University Co-Op students. The work period is from January 2027 to June 2027. This is a full-time, 40 hours per week position with 5 days in office. ProFound Therapeutics is seeking an innovative and highly motivated Co-Op with experience in cell biology and/or disease biology to play a vital role in the company’s Cardiovascular, Metabolic & Neuroscience team. Under the supervision of senior scientists on the Cardiovascular, Metabolic & Neuroscience team, this individual will receive structured training and hands-on experience in in vitro cell-based assays supporting ongoing mid- and high-throughput functional projects. This individual will contribute scientific and technical expertise to a multidisciplinary team, emphasizing conceptualization, experimentation, data analysis, presentation, and strategic planning. The ideal candidate for this position will have coursework or early research experience in cell biology, physiology, or a related discipline and be enthusiastic and capable of working in a multidisciplinary (e.g. genomics, bioinformatics, protein biochemistry) team in the biosciences. The candidate should be able to work independently and as part of a team in a fast-paced entrepreneurial setting. The Co-Op is designed to complement the candidate’s academic training and provide exposure to industry-based research and therapeutic development.
Requirements
- Pursuing a Bachelor’s or Master’s degree in cell biology, biology, physiology, biochemistry, or a related field
- Coursework or hands-on research experience in mammalian cell culture and basic laboratory techniques, and attention to detail
- Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner
- Strong collaborative skills with evidence of working in a team
Nice To Haves
- Prior industry or academic research co-op experience in cell biology or a related discipline
- Experience with mammalian cell culture, including human primary cells
- Coursework or research exposure to metabolic, cardiovascular, or neurological disease biology
- Familiarity with microscopy or imaging-based assays (e.g. high-content imaging, immunofluorescence)
- Exposure to cell based assay development
- Confident execution, focused and team-oriented with an ability to thrive in an entrepreneurial environment
- Experience with data analysis using Graphpad Prism and Microsoft Excel
Responsibilities
- Serve as a contributor to the Cardiovascular, Metabolic & Neuroscience team, whose mission is to discover new therapeutics and validate new therapeutic targets
- Collaborate with senior scientists to support ongoing cardiovascular, metabolic, and neuroscience projects
- Culture, differentiate, and maintain human primary cells and cell lines (e.g. adipocytes, endothelial cells/HUVECs, hepatocytes, and skeletal muscle cells)
- Assist with the development and testing of functional assays using human primary cells for low-, mid-, and high-throughput applications via high-content imaging and confocal immunofluorescence (IF)
- Support disease-relevant readouts, including mitochondrial function, endothelial barrier/permeability, glucose uptake, and lipolysis
- Prepare reagents for functional assays and screens, including peptide reconstitution and aliquoting
- Analyze, interpret, and present experimental data (e.g. GraphPad Prism, Excel) at team meetings and in reports
- Organize and maintain experimental records in Benchling for review
- Report experimental plans and results to the scientific team
- Proactively review literature to contribute to new ideas and methods/technologies for discovery and therapeutic areas
Benefits
- Compensation reflects the real work you take on.
- Retirement benefits may be available after completing a set number of hours.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Education Level
No Education Listed
