Bioprocess Engineer, Cell Production & Process Development

United Therapeutics Corporation•Manchester, NH

2d•Onsite

About The Position

United Therapeutics (Nasdaq: UTHR) is a public benefit corporation dedicated to developing novel pharmaceutical therapies and technologies to expand the availability of transplantable organs. Founded in 1996, the company has developed six FDA-approved therapies for rare diseases and is now focused on creating manufactured organs to address the shortage of kidneys, hearts, lungs, and livers for transplant. The Bioprocess Engineer, Cell Production and Process Development role is crucial in developing and scaling robust cell production processes to support these ambitious advances in regenerative medicine, aiming to provide a brighter future for patients.

Requirements

Bachelor's degree in biomedical science, cell biology or related field with 2+ years of relevant industry experience with prior experience in iPSC culture and bioreactor cell production OR Master's degree with 1+ years of relevant industry experience with prior experience in iPSC culture and bioreactor cell production
Experience with cell bioreactor culture, preferably Sartorius Ambr/B-DCU systems and/or vertical wheel bioreactors with scales up to 10L+
Experience with automated cell processing equipment such as CliniMACS Plus, LOVO, Cue, Sepax, Sefia, Rotea or others
Knowledge in transfer of R&D cell expansion methods to GMP
Proficient with appropriate word processing, spreadsheet, presentation and related standard software; Experience with laboratory instrumentation and data software
Ability to accommodate a non-traditional work schedule (e.g. Sun-Thu, Tue-Sat)

Nice To Haves

Master’s Degree in biomedical science, cell biology or related field
Strong working knowledge of cellular process development

Responsibilities

Contribute to the production effort to provide sufficient cells for R&D cellularization and tissue engineering efforts of 3D printed scaffolds
Execute process development studies to scale-up iPSC differentiation processes to multiple cell types and develop robust, cGMP manufacturing processes
Assist in developing, writing, and reviewing laboratory methods and protocols
Assist in evaluating new technologies for future process development
Support tech transfer activities from outside collaborators to internal laboratory and from internal PD efforts to cGMP manufacturing sites, as needed
Support the evaluation of laboratory equipment
Foster and leverage synergistic interactions with other sub-groups in Organ Manufacturing (e.g., Bioink, Scaffold Production, Cellularization), as needed
Support the creation of data for scientific publications and presentations at scientific conferences
Perform other duties as assigned