Biomedical Technician

Cedars-Sinai Medical Center•Beverly Hills, CA

1d•Onsite

About The Position

The Applied Genomics, Computation & Translational Core (AGCT) is seeking a Biomedical Technician to join their team. The AGCT Core is an automated, high-throughput genomics facility utilizing the latest next-generation sequencing technologies, specializing in single-cell and spatial omics. They offer expertise in various sequencing platforms and provide comprehensive support from sample preparation to bioinformatics analysis, including custom computational solutions and results interpretation. The Biomedical Technician will contribute to the laboratory sciences team, working independently under direct supervision. Responsibilities include performing laboratory benchwork according to Standard Operating Procedures (SOPs), accurate documentation, quality control of RNA and DNA samples, and contributing to project success through communication and attention to detail. The role involves working with state-of-the-art technologies, performing next-generation sequencing library preparation and sequencing.

Requirements

Associate’s Degree or College Diploma in Biology, Biochemistry, or a related science/engineering field
Minimum of 1 year of experience in a laboratory or biotechnology environment

Nice To Haves

Bachelor’s Degree in Biology, Biochemistry, or a related science/engineering field
Experience with biomedical equipment, including maintenance and/or testing

Responsibilities

Performs a variety of project-specific process development tasks for multiple clients following standard operating procedures (SOPs).
Maintains good documentation in laboratory notebooks, data record/transfer, SOPs, and batch records.
Drafts standard operating procedures and maintains computer database.
Verifies samples received, logs samples into systems, and may transport to appropriate environment within the facility for storage following SOPs.
Performs lab maintenance duties, including glassware cleaning and sterilization.
Maintains lab equipment and related records.
Prepares cGMP production room, maintains material inventories, and places orders for equipment and supplies.
Assists in the operation of specialized equipment and machinery.
Ensures all activities comply with regulatory guidelines and safety standards, as appropriate.
Construction of next generation sequencing libraries for bulk cell, single cell, and/or spatial omics using commercially available reagent kits.
Illumina short-read sequencing and/or Oxford Nanopore Technologies long-read sequencing of NGS libraries.
DNA/RNA QC via fluorescent quantification and automated electrophoresis.
Operation of state-of-the-art genomics equipment including NGS sequencers, automated liquid handlers, and tissue imagers, as well as standard laboratory equipment such as thermal cyclers, centrifuges, and qPCR machines.
Mathematical calculations, including fold dilution, normalization, and conversions.
Understand, analyze, and interpret DNA/RNA/NGS library/sequencing QC results.
Liaise with post-doctoral, doctoral, and staff researchers, clinical investigators, and principal investigators to provide quality customer service.
Handle multiple demands and/or manage complex and competing priorities, pivoting as needed based on current needs in a dynamic environment.
Apply advanced knowledge of science/learning/specialized intellectual instructions to analyze, interpret, or make deductions from varying facts or circumstances.
Provide and/or support a level of work excellence and accuracy; recognize and address flaws or errors that others may overlook.
Regular oral and written communication with team members and team lead.
Accurate and detailed electronic documentation of work performed and results obtained.
Work independently as part of a team under direct supervision of a team lead.
Observe and comply with all safety standards and procedures.