Biologist (3-5 years)

Real Soft•Boston, MA

About The Position

Eli Lilly’s Cardiometabolic Renal Therapeutic Area focuses on discovering biologic, small-molecule, and genetic therapeutics for diabetes, obesity, and associated complications. The Obesity research group is seeking a skilled and motivated biologist to contribute to drug discovery and development, particularly anti-obesity therapeutics. The role applies in vivo pharmacology and complementary laboratory skills to support discovery efforts and pipeline projects, executing key laboratory capabilities and collaborating with scientists across departments to meet project and department goals. The position involves planning and independently carrying out in vivo experiments to support preclinical characterization of targets and pathways that regulate energy balance. It also includes rodent procedures, metabolic assessments, molecular and biochemical analysis of ex vivo samples, data analysis and reporting, and participation in cross-functional teams. Work must comply with Lilly Research Policies, and required training must be completed within specified timeframes. The posting describes this as a temporary contractor assignment.

Requirements

B.S. and/or M.S. in biology or a closely related field.
At least 3 years of laboratory experience.
Strong in vivo pharmacology background.
Ability to work independently and collaboratively on cross-functional teams.
Strong communication skills and experience presenting data in a team environment.

Nice To Haves

Background in the biology and physiology of energy balance regulation and metabolic disease.
Experience with immunohistochemistry, brain sectioning, and confocal or fluorescence microscopy imaging.

Responsibilities

Plan and independently execute in vivo experiments to support preclinical characterization and evaluation of targets and pathways that regulate energy balance.
Handle rodents and administer doses through multiple routes, including oral (PO), intraperitoneal (IP), subcutaneous (SQ), and intravenous (IV).
Collect blood, including by cardiac puncture, and perform perfusion and tissue collection.
Conduct metabolic assessments, including food intake measurements, glucose tolerance tests (GTT), and insulin tolerance tests (ITT).
Perform molecular and biochemical assessments on ex vivo samples.
Work independently in a team-oriented laboratory environment and with cross-functional project teams.
Maintain accurate records, analyze data independently, and report findings in written and oral formats.
Comply with Lilly Research Policies and complete required training within specified timeframes.
Conduct experiments to identify and validate drug targets.
Support assay design, optimization, validation, and data analysis.
Design and execute molecular and cell biology experiments.
Troubleshoot and analyze complex data in support of drug discovery projects.
Present results and conclusions orally and in writing.