Biologist (51819)

GAP SOLUTIONS INCBethesda, MD
$75,000 - $135,000Onsite

About The Position

The Biologist will independently provide support services to satisfy the overall operational objectives of the NIH Clinical Center, Department of Transfusion Medicine, Human Leukocyte Antigen Laboratory within the National Institutes of Health.

Requirements

  • Master’s Degree in Genetics, Microbiology, or similar field of study
  • American Board of Histocompatibility and Immunogenetics certification eligible
  • Experience with MS Office Suite

Nice To Haves

  • Ability to communicate effectively, orally and in writing, with non-technical and technical staff
  • Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects

Responsibilities

  • Perform specimen processing
  • DNA extraction and quantitation utilizing various manual and automated methods
  • Molecular HLA typing utilizing polymerase chain reaction (PCR), sequence specific primer (SSP), sequence specific oligonucleotide (SSO) technology, and sequenced based typing (SBT)
  • Molecular HLA typing utilizing next generation sequencing
  • Next generation sequencing data analysis
  • Agarose preparation and gel electrophoresis; photo-documentation of results
  • Interpretation of all HLA typing results
  • Support the general HLA staff in communication with transplant groups and appropriate documentation
  • Perform troubleshooting on current HLA analysis software and database management systems and all facets of laboratory
  • Various HLA antibody screening and identification methods and interpretation
  • Work with staff on the identification of unusual HLA antibody and typing patterns; maintain leadership and support role to encourage staff members to understand the complexities of antibody identification and the other work they perform
  • Perform final review analysis process and determine any discrepancies which need resolution
  • Participate in the review and audit of laboratory records and standard operating procedures (SOPs) in order to improve the efficiency and effectiveness of the laboratory; maintain related documents
  • Participate in the review of QC and quality assurance records to assure that the laboratory is maintaining necessary levels of accreditation
  • Maintain documents related to keeping maintenance documentation and monitoring of quality assurance practices
  • Provide a leadership role in taking the initiative to implement changes upon request
  • Work with staff on test assay development, validation and implementation of new equipment and reagents in the sequencing area in order to provide a more efficient high-throughput test; maintain related documents
  • Collaborate with staff on the evaluation of any new reagents assays for antibody detection that may benefit the laboratory
  • Perform validation and recording of specimens in all appropriate software-based applications
  • Apply troubleshooting skills in the areas of the laboratory software applications and instrumentation
  • Monitor the quality assurance practices in all aspects of laboratory work
  • Coordinate the teaching process of fellows, students, and other laboratory staff regarding new procedures and techniques
  • Work on various research projects through the laboratory in order to document potential clinical application in the laboratory
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