Biologist (Genomics) (50865)

GAP SOLUTIONS INCBaltimore, MD
$70,000 - $140,000Onsite

About The Position

The National Institutes of Health requires contractor support for laboratory and computational analysis of genomic and epigenomic data. The work supports ongoing research involving genotyping, long-range sequencing, and DNA methylation profiling at the National Institute on Aging (NIA) within the National Institutes of Health (NIH).

Requirements

  • Masters Degree in Biology or similar field of study
  • At least 2 years of experience
  • Proficiency in R and at least one scripting language
  • Experience with QC and data visualization
  • Familiarity with genomic data formats (FASTQ, BAM, VCF)
  • Strong communication skills, both oral and written.
  • Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects.

Responsibilities

  • Evaluate: Read quality, coverage, and depth and Sample integrity and contamination Flag anomalies and provide preliminary interpretation.
  • Perform DNA extraction from blood, tissue, or cultured cells using established protocols.
  • Conduct genotyping assays (e.g., SNP arrays, PCR-based methods)
  • Support long-range sequencing workflows (e.g., library prep and sequencing using long-read platforms such as PacBio or Oxford Nanopore).
  • Perform DNA methylation assays (e.g., bisulfite conversion, array-based or sequencing-based methods).
  • Execute established QC pipelines for sequencing and genotyping data.
  • Compile and document QC metrics in standardized formats.
  • Modify existing scripts and pipelines to support project needs.
  • Perform data analysis using: R (statistical analysis and visualization) and Scripting (Python, Bash, or equivalent)
  • Conduct: Variant calling and basic annotation and DNA methylation data processing and analysis and Data integration across datasets when directed
  • Maintain accurate laboratory notebooks and electronic records.
  • Identify routine technical issues and implement standard troubleshooting steps.
  • Prepare: Summary tables and figures and Written summaries of methods and results
  • Present findings in internal meetings to NIH staff
  • Contribute to draft reports, manuscripts, or project updates.
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