Biological Scientist IV

University of Florida•Gainesville, FL
•$83,700 - $92,200

About The Position

The University of Florida’s Diabetes Institute (UFDI) is seeking a Biological Scientist IV to provide critical support for tissue sample processing and data generation for type 1 diabetes research. The role applies expertise in molecular and single-cell biology to research using human tissue samples and supports laboratory studies in type 1 diabetes genetics, human immune development, and adaptive immunity. The position oversees spatial transcriptomics operations, processes and prepares human tissue samples for assays, and manages sample-processing workflows for next-generation sequencing, flow cytometry, and immunofluorescence image data. It directs research studies for the UFDI Spatial Transcriptomics and Multi-Omics Research Group, supervises scientists and students, coordinates scientific services and laboratory SOPs, and leads data management and analysis pipeline development for the UFDI multi-omics core. Additional work includes manuscript development, study reporting, grant-writing participation, presenting findings, maintaining laboratory records and regulatory compliance, and staying current with relevant advances in histology, imaging, and image processing. This is a time-limited position.

Requirements

  • Bachelor's degree in biology or a related field and thirteen years of experience; or a master's degree in biology or a related field and eleven years of experience; or a doctoral degree in biology or a related field and eight years of experience.
  • Upload a cover letter and resume to be considered.

Nice To Haves

  • Experience designing and troubleshooting fluorophore-antibody-filterset combinations and microscope parameters to obtain interpretable signal-to-noise image acquisition.
  • Experience with tissue-clearing approaches and 3D image acquisition and analysis.
  • Knowledge of coding environments, cloning repositories, command-line/terminal execution, Linux OS, and building code from source.
  • Knowledge and education covering major systems in human physiology and pathophysiology.
  • A consistent history of productivity evidenced by contributions to publications, grants, abstracts, and presentations.

Responsibilities

  • Direct, manage, and execute research studies for the UF Diabetes Institute Spatial Transcriptomics and Multi-Omics Research Group.
  • Directly supervise scientists, postdoctoral researchers, graduate students, and undergraduate students across all facets of research studies.
  • Develop methods for spatial biology research in type 1 diabetes.
  • Monitor and operate specialized multi-omic imaging platform equipment.
  • Create and execute computational approaches for data analysis and visualization.
  • Coordinate scientific services relating to spatial transcriptomics, scRNAseq, and high-parameter imaging platforms for UFDI and collaborating College of Medicine members.
  • Develop and oversee laboratory SOPs and ensure proper processing of cell and tissue samples for the UFDI multi-omics core.
  • Lead data management and data-analysis pipeline development for the UFDI multi-omics core.
  • Manage UF Hipergator resources and develop the UFDI codebook for multi-omics activities, sharing resources on GitHub or other applicable platforms.
  • Develop manuscripts and write research-related content.
  • Generate timely reports on study activities for the PI and UFDI leadership, including progress reports for the NIH, FDOH, and other funding authorities.
  • Participate in grant writing for new funding opportunities.
  • Present research findings at institutional, governmental, and international scientific meetings.
  • Prepare and submit manuscripts for publication in scientific journals.
  • Maintain accurate laboratory records.
  • Perform and supervise laboratory maintenance and upkeep in accordance with EH&S and other regulatory requirements for handling chemical and biohazardous materials.
  • Stay current with advances in histology, imaging, and image processing through journal articles, networking, seminars, and conferences.
  • Perform other duties as assigned by the project manager and principal investigator.
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