Bioinformatics Scientist

Predicine, Inc • Hayward, CA

1d • $119,200 - $149,000 • Onsite

About The Position

Predicine, Inc. in Hayward, CA seeks a Bioinformatics Scientist to perform research and development of novel DNA methylation normalization algorithms, optimize DMFR pipelines, and analyze next-generation sequencing data.

Requirements

• Master’s degree or foreign equivalent in Biology, Biomedical Engineering, Bioinformatics, or a related field plus 3 years of experience in the job offered or an R&D related occupation.
• Alternatively, a Doctorate degree or foreign equivalent in Biology, Biomedical Engineering, Bioinformatics, or a related field.
• Strong research ability.
• Solid knowledge in developing and validating analytical approaches.
• Solid knowledge in interpreting complex biological data.
• Solid knowledge in applying research insights to projects.
• Any suitable combination of experience of education, training, or experience is acceptable.

Responsibilities

• Develop, test, and optimize vertical and horizontal DNA methylation normalization algorithms, evaluating different mathematical formulas and parameters to improve accuracy and robustness.
• Validate methylation algorithms and updated DMFR (Differentially Methylated Fragment Regions) pipelines using reference samples and diverse client datasets.
• Debug, update, and maintain bioinformatics pipelines to ensure reproducible and scalable post-analysis workflows across multiple projects.
• Design and implement post-pipeline analyses, including generating results, figures, and statistical summaries for client-specific and research-driven projects.
• Collaborate with wet lab teams to support assay development, validation, troubleshooting, and concordance studies between different sequencing platforms and experimental conditions.
• Conduct quality control and statistical analysis for sequencing data, including sensitivity, conversion rates, and comparative assessments to guide experimental and pipeline improvements.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior