Bioinformatics Analyst III

Theiagen Genomics•Denver, CO

1d•$110,000 - $120,000•Remote

About The Position

Theiagen is seeking a Bioinformatics Analyst III to serve as a senior scientific and operational leader within our Public Health Team, reporting to the Public Health Team Lead. This role will independently lead complex and high-impact initiatives, serve as a primary owner for select partner engagements and projects, provide scientific oversight and mentorship across teams, and support the continued growth and scalability of Theiagen’s pathogen genomics services and operations.

Requirements

Masters or doctoral degree in bioinformatics, biostatistics, computer science, microbiology, molecular biology, or related field.
7+ years of experience in bioinformatics analysis, with expertise in NGS and multi-omics data.
Experience in programming languages such as SQL/Python/R.
Experience with bioinformatics tools, databases, and workflow management systems (Nextflow, Snakemake, WDL).
Demonstrated expertise applying bioinformatics tools and workflows to answer complex biological questions, particularly in pathogen genomics.
Advanced proficiency in using bioinformatics tools for tasks such as genome assembly, annotation, taxonomic classification, and antimicrobial resistance detection.
Proficiency with genomic epidemiology methods, including phylogenetics, outbreak investigation tools, and MLST typing.
Proven ability to lead and manage multiple projects independently or within a collaborative team environment.
Excellent written and verbal communication, with experience presenting technical results to diverse audiences.
Effective judgment and advanced problem-solving skills with minimal supervision.
Strong motivation and demonstrated impact in public health initiatives.

Nice To Haves

Comprehensive knowledge of public health laboratory processes and workflows, including validation and verification of bioinformatics workflows for decision-making.
Expertise in interpreting bioinformatics results and providing actionable public health insights.
Significant experience analyzing pathogen genomics datasets for public health applications (e.g., SARS-CoV-2, Mycobacterium tuberculosis, antimicrobial resistance, or HAIs).
Advanced experience with cloud-based bioinformatics platforms (e.g., Terra.bio, Galaxy) and workflow orchestration tools (e.g., Nextflow, WDL, or Snakemake).
Hands-on expertise in using visualization and reporting tools to clearly communicate results to stakeholders.
Proficiency in shell scripting and working in UNIX/Linux environments.
Experience mentoring junior team members and fostering technical excellence.

Responsibilities

Serve as a pathogen genomics subject matter expert for public health and other applications.
Provide scientific oversight and sign-off authority for analyses, reports, presentations, and partner deliverables.
Guide interpretation of complex or non-routine analytical results.
Ensure scientific rigor, reproducibility, and alignment with partner needs.
Support development and evaluation of analytical methods, workflows, and tools.
Independently lead novel, ambiguous, or high-complexity projects from initiation through delivery.
Serve as primary owner for partner engagements and specialized initiatives.
Coordinate across analysts, developers, project managers, and stakeholders to drive execution.
Develop implementation strategies, design documentation, and operational approaches for new project types.
Act as escalation point for non-routine analytical and operational challenges.
Lead partner-facing meetings and communications independently.
Build trusted relationships with public health and external partners.
Identify partner needs and translate them into actionable analytical and technical solutions.
Present findings, recommendations, and project updates to technical and non-technical audiences.
Support strategic discussions regarding project direction and delivery.
Support Team Leads in alignment of analytical work with organizational priorities and operational strategy.
Support Team Leads in scaling operations and distributing leadership responsibilities.
Contribute to planning discussions regarding current and future services, and idea development for services expansion/improvement.
Collaborate across teams to improve consistency, coordination, and delivery quality.
Communicate technical concepts clearly across interdisciplinary teams.
Mentor Analyst I and II staff through onboarding, troubleshooting, and professional development.
Lead training initiatives and contribute to development of best practices and SOPs.
Identify opportunities for workflow optimization, automation, and operational efficiency.
Support knowledge-sharing and development of internal technical standards.
Foster technical excellence and collaborative problem solving across teams.
Define and translate product vision, roadmap, and priorities into actionable initiatives and continuously optimize direction based on user feedback, performance metrics, and organizational goals.
Define and validate product acceptance criteria, ensuring deliverables meet functional and quality standards while monitoring product performance and user experience to drive continuous improvement.
Serve as the primary liaison between stakeholders and the development team, ensuring clear communication of requirements, and supporting the team to successfully deliver sprint goals.
Support refinement and prioritization of the product backlog by defining clear requirements, user stories, and acceptance criteria; collaborate with cross-functional stakeholders to incorporate customer and business feedback; and communicate product priorities, timelines, and risks to ensure delivery aligns with business value.

Benefits

Paid Time Off
Fully remote work (Must hold citizenship for where you plan to work from, role does not offer sponsorship)
Company supplied computer
Medical, Dental, Vision coverage/stipend
401(k) with company match
Flexible Spending Accounts
Employee Assistance Program
Employee Discount Program
Competitive salary
opportunities for professional development.