Bioinformaticist

Battelle • Columbus, OH

12d • Hybrid

About The Position

We are seeking a systems biologist with experience integrating biology and bioinformatics to identify how biological systems change over time and under varying conditions to develop solutions to health and environmental issues. This position will conduct differential analysis of methylation, transcriptomics, ATAC-Seq, and single cell multi-ome and integrate the data to discover biomarkers for diseases and targets for drug or probiotic treatments. The candidate must be a US citizen and eligible to obtain and maintain a SECRET level U.S. Government security clearance.

Requirements

• Ph.D. OR a M.S. with at least 2 years of relevant industry experience. Degree must be in bioinformatics, biology, genetics, computer science, mathematics, or a related scientific discipline.
• Expertise in analysis, interpretation and bioinformatics research on large multivariate molecular profiling datasets to include methylation, ATACseq, transcriptomics, and single cell multiome.
• Experience developing and integrating data and tools to distill knowledge from large datasets.
• Excellence in relevant programming languages (ideally Python and/or R)
• A track record demonstrating scientific creativity, collaboration, and independence
• Must be a US citizen with the ability to obtain and maintain required government security clearances as a condition of employment.
• The ability to work in a team environment
• Excellent written and oral communication skills

Nice To Haves

• Experience in machine learning and biostatistics
• Experience in pathway analysis
• Experience with epigenetics systems biology and/or epigenetics bioinformatics
• Experience analyzing proteomics and metabolomics data sets

Responsibilities

• Working with exome sequencing, methylation arrays, methylation sequencing, ATAC-seq, miRNA-seq, RNA-seq, and ChIP-Seq bioinformatic workflows.
• Working with high throughput scRNA-Seq, scATAC-Seq analysis using existing single cell analysis software like Seurat and established single cell pipelines.
• Using methods like principal component analysis, spectral decomposition, t-SNE, UMAP for data visualization and clustering techniques like k-means clustering, agglomerative hierarchical clustering, graph partitioning etc. for cell type annotations.
• Regulatory network analysis and genetic annotation of data.
• Participating in collaborative projects with other leading academic research and industry collaborators on computational analysis of high-dimensional, cell and molecular profiling data to advance precision microbiome efforts.
• Perform analyses in a transparent manner and to clearly communicate analysis results and methods with collaborating researchers who may or not have computational backgrounds.
• Additionally, the selected candidate will be expected to guide and train other staff, as well as to perform certain administrative functions, as necessary, to ensure smooth functioning of experiments and timely distribution of program deliverables.
• Limited domestic and potential international travel is anticipated.

Benefits

• Live an Extraordinary Life
• We care about your well-being, not just on the job. Battelle offers comprehensive and competitive benefits to help you live your best life.
• Balance life through a compressed work schedule: Most of our team follows a flexible, compressed work schedule that allows for every other Friday off—giving you a dedicated day to accomplish things in your personal life without using vacation time.
• Enjoy enhanced work flexibility, including a hybrid arrangement: You have options for where and when you work. Our Together with Flexibility model allows you to work 60% in-office and 40% remote, with Monday and Tuesday as common in-office days, dependent on team and position needs.
• Take time to recharge: You get paid time off to support work-life balance and keep motivated.
• Prioritize wellness: Stay healthy with medical, dental, and vision coverage with wellness incentives and benefits plus a variety of optional supplemental benefits.
• Better together: Coverage for partners, gender-affirming care and health support, and family formation support.
• Build your financial future: Build financial stability with an industry-leading 401(k) retirement savings plan. For most employees, we put in 5 percent whether you contribute or not, and match your contributions on top of that.
• Advance your education: Tuition assistance is available to pursue higher education.
• A Work Environment Where You Succeed
• For brilliant minds in science, technology, engineering and business operations, Battelle is the place to do the greatest good by solving humanity’s most pressing challenges and creating a safer, healthier and more secure world.
• You will have the opportunity to thrive in a culture that inspires you to:
• Apply your talent to challenging and meaningful projects
• Receive select funding to pursue ideas in scientific and technological discovery
• Partner with world-class experts in a collaborative environment
• Nurture and develop the next generation of scientific leaders
• Give back to and improve our communities
• Vaccinations & Safety Protocols
• Battelle may require employees, based on job duties, work location, and/or its clients’ requirements to follow certain safety protocols and to be vaccinated against a variety of viruses, bacteria, and diseases as a condition of employment and continued employment and to provide documentation that they are fully vaccinated. If applicable, Battelle will provide reasonable accommodations based on a qualified disability or medical condition through the Americans with Disabilities Act or the Rehabilitation Act or for a sincerely held religious belief under Title VII of the Civil Rights Act of 1964 (and related state laws).
• Battelle is an equal opportunity employer. We provide employment and opportunities for advancement, compensation, training, and growth according to individual merit, without regard to race, color, religion, sex (including pregnancy), national origin, sexual orientation, gender identity or expression, marital status, age, genetic information, disability, veteran-status veteran or military status, or any other characteristic protected under applicable Federal, state, or local law. Our goal is for each staff member to have the opportunity to grow to the limits of their abilities and to achieve personal and organizational objectives. We will support positive programs for equal treatment of all staff and full utilization of all qualified employees at all levels within Battelle.
• The above statements are intended to describe the nature and level of work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, activities and skills required of staff members. No statement herein is intended to imply any authorities to commit Battelle unless special written permission is granted by Battelle's Legal Department.
• For more information about our other openings, please visit www.battelle.org/careers

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level