Bioinformatician I

Mass General Brigham•Somerville, MA

6d•Hybrid

About The Position

The Channing Division of Network Medicine at Brigham and Women’s Hospital, Boston are looking for exceptional candidates to work with Dr Dawn Demo on epignome projects at CDNM. The works involves a wide variety of data management challenges of complex data sets, including genomic scale next-generation sequencing data and Data processing or curation. Our projects involve interrogation of the genome, transcriptome and epigenome data utilizing machine learning analysis tools and data analysis pipelines. The Bioinformatician will be developing and supporting the complex bioinformatics infrastructure needed for the wide range of data collection, transformation of data, and analysis requirements that will integrate across a wide range of skills and techniques. The Bioinformatician is required to design, create, support tools and software analysis pipelines including secure dissemination of information generated.

Requirements

MS in Bioinformatics, Computer Science, or biological engineering.
Understanding of programming with agile development methods.
Ability to apply statistical and machine learning techniques to solve ‘big data’ problems.
Experience in programming with R, Python [Pandas].
Understanding the use of bioinformatics tools including common methylation tools [Minfi, EpiMix].
Understanding the use of bioinformatics tools including common OMICs Data [dna, rna, methylation, 16S, metabolomics].
Experience with Databases (Postgres) and DB Design.
Familiarity with Docker; Kubernetes; Snakemake or Nextflow.
Ability to work in a highly collaborative and intellectually challenging environment.
Knowledge of Linux (Ubuntu).
Excellent oral and written communication skills.

Responsibilities

Develop and support complex bioinformatics infrastructure for data collection, transformation, and analysis.
Design, create, and support tools and software analysis pipelines.
Ensure secure dissemination of generated information.
Perform technology watch and contribute to the strategy and evolution of existing services and future architecture.
Work independently.