Bioinformatician I- Immunology and Immunotherapy

Mount Sinai Health SystemNew York, NY

About The Position

The Bioinformatician I supports translational and clinical research within an Immune Monitoring Center by analyzing high-plex immunologic datasets generated across diverse diseases, tissues and patient cohorts. This role works closely with immunologists, clinicians, wet-laboratory scientists, and computational researchers to characterize immune-cell populations, cellular states, regulatory programs, and tissue-specific immune responses. The position is responsible for the end-to-end processing and analysis of bulk, single-cell, multiomic, and spatial sequencing data, from raw-data processing and quality assessment through biological interpretation and communication of findings. A major focus of the role is translating complex sequencing data into biologically meaningful insights related to immune activation, inflammation, tissue microenvironments, disease mechanisms, treatment response, and potential biomarkers.

Requirements

  • Analysis of high-plex immunologic datasets generated across diverse diseases, tissues and patient cohorts.
  • Close collaboration with immunologists, clinicians, wet-laboratory scientists, and computational researchers.
  • Characterization of immune-cell populations, cellular states, regulatory programs, and tissue-specific immune responses.

Responsibilities

  • End-to-end processing and analysis of bulk, single-cell, multiomic, and spatial sequencing data.
  • Raw-data processing and quality assessment.
  • Biological interpretation and communication of findings.
  • Translating complex sequencing data into biologically meaningful insights related to immune activation, inflammation, tissue microenvironments, disease mechanisms, treatment response, and potential biomarkers.
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