Biochemist III

Bureau Veritas•Indianapolis, IN

1d•$31 - $34

About The Position

The Biochemist III supports the early molecule discovery team by designing and implementing robust biochemical and biophysical assays for hit identification, hit triage, and mechanism-of-action characterization across diverse molecular targets. The role combines hands-on laboratory work with assay development, automation, and high-throughput screening to accelerate early-stage discovery programs. The position typically works Monday through Friday, 40 hours per week, with flexibility needed to meet departmental needs and complete other assigned projects. The Biochemist III performs testing independently with little or no management guidance, reports and records test data promptly, troubleshoots escalated technical issues, and may write or edit procedures. The role follows client and company quality, safety, chemical hygiene, health, security, environmental, and applicable regulatory requirements.

Requirements

Master’s degree in Chemistry, Biochemistry, or a closely related field.
At least 2 years of related experience.
Experience across diverse target classes, including enzymes and protein–protein interactions.
Familiarity with fluorescence-, luminescence-, and mass spectrometry-based assays.
Ability to design experiments that balance throughput, sensitivity, and robustness.
Proficiency with Windows, Word, and Excel.
Attention to detail and ability to adhere to company values.
Ability to present facts and recommendations effectively.
Technical problem-solving and process-improvement skills.
Strong interpersonal skills, including approachability, relationship building with internal and external contacts, initiative, and adaptability.
Understanding of experimental design and ability to conduct necessary background research.
An equivalent combination of education and experience may be accepted.

Responsibilities

Design, develop, and validate biochemical and biophysical assays for hit identification, hit triage, and mechanism-of-action characterization.
Perform biochemical assays using TR-FRET, fluorescence polarization (FP), AlphaLISA/AlphaScreen, luminescence, and ELISA formats.
Prepare assay reagents, protein dilutions, substrate stocks, and compound serial dilutions.
Execute enzyme activity, protein–protein interaction, and binding assays with guidance.
Run assays in 384- and 1536-well microplate formats.
Operate and maintain plate readers and associated software.
Analyze, interpret, and present data to internal project teams to guide early-stage molecule discovery.
Collaborate with chemistry, structural biology, and computational teams to support target characterization and screening strategies.
Follow client and Bureau Veritas Consumer Products Services, Inc. quality, safety, chemical hygiene, health, security, and environmental guidelines and procedures, including BV-CPS Quality System requirements.
Accurately report and record test data in electronic or handwritten notebooks in a timely manner.
Perform testing independently with little or no guidance from management.
Identify, troubleshoot, and solve escalated technical issues.
Write or edit procedures as requested.
Complete other duties as defined by the manager, department needs, and workload.