Bioanalytical Scientist

Alcon•Durham, CA

7d•Onsite

About The Position

At Alcon, we're passionate about enhancing sight and helping people see brilliantly. With more than 25,000 associates, we innovate fearlessly, champion progress, and act swiftly to impact global eye health. We foster an inclusive culture, recognizing your contributions and offering opportunities to grow your career like never before. Together, we make a difference in the lives of our patients and customers. Are you ready to join us? Alcon is looking to hire a Bioanalytical Scientist (Sr. Associate I) within, Preclinical Development to lead bioanalytical strategy supporting small‑molecule discovery, preclinical and regulatory development programs. This role serves as a key scientific interface across internal stakeholders and external partners, providing expert guidance on bioanalytical method development, execution, and interpretation for small‑molecule programs. The successful candidate will bring strong technical expertise, strategic thinking, and hands‑on leadership to ensure high‑quality, fit‑for‑purpose bioanalytical support aligned with program and regulatory needs. This role is on-site in our Durham, NC location.

Requirements

Bachelor’s Degree or Equivalent years of directly related experience (or high school +10 yrs; Assoc.+6 yrs; M.S.+0 yrs)
The ability to fluently read, write, understand and communicate in English.
2 Years of Relevant Experience.

Nice To Haves

5+ Years of Relevant Experience
Demonstrated expertise in LC‑MS/MS and mass‑spectrometry‑based quantitative bioanalysis.
Strong background in separation science and hyphenated analytical techniques.
Experience operating in regulated environments, with working knowledge of GLP/GCP requirements.
Proven ability to provide scientific leadership across multiple programs and priorities.
Strong written and verbal communication skills with the ability to convey complex data to diverse audiences.
Experience overseeing CROs and outsourced small‑molecule bioanalytical programs.
Familiarity with Phoenix WinNonlin for noncompartmental and PK data analysis.
Working knowledge of ocular PK modeling approaches and ophthalmology‑relevant modeling tools (e.g., ocular compartmental models, exposure–response interpretation).
Track record of innovation and modernization of bioanalytical workflows.

Responsibilities

Define and drive small‑molecule bioanalytical strategy across discovery, preclinical, and early clinical development.
Provide expert input on study design, method selection, data interpretation, and regulatory expectations for small‑molecule programs.
Develop and implement stage‑appropriate LC‑MS/MS‑based bioanalytical methods for quantification of small molecules in a variety of biological matrices.
Apply advanced analytical and separation techniques to address complex scientific questions related to exposure, metabolism, stability, and biotransformation.
Identify, evaluate, and implement new technologies and workflows to enhance bioanalytical efficiency and data quality.
Author and review bioanalytical sections of reports supporting INDs, regulatory submissions, patents, and publications.
Serve as the bioanalytical scientific representative on cross‑functional project teams, including partnered programs.
Analyze, interpret, and clearly communicate bioanalytical and DMPK data to project teams, senior leadership, and external collaborators.
Ensure consistent data quality, integrity, and documentation in accordance with GLP/GCP expectations and internal standards.
Contribute to continuous improvement of bioanalytical processes, infrastructure, and resource planning.