Associate Scientist

Bristol Myers SquibbSan Diego, CA
Onsite

About The Position

The Protein Homeostasis Thematic Research Center (TRC) at Bristol Myers Squibb (BMS) is a fundamental Oncology research engine focused on delivering oncology and hematology therapeutics. The TRC specializes in exploiting BMS' expertise in protein degradation to discover and develop therapies targeting tumor-intrinsic vulnerabilities and resistance mechanisms to existing cancer therapeutics, aiming to address previously undruggable protein classes. Within the TRC, the Translational Pathology group supports the company’s Oncology drug discovery and translational pathology efforts across multiple research units and sites. This group provides pathobiology scientific expertise, diagnostic consultation, and histopathology technical support under the leadership of an MD pathologist. Their primary responsibilities include collaborating with research scientists to support tissue-based target validation, animal model studies, and biomarker research from Discovery through Proof-of-Concept studies.

Requirements

  • Bachelor’s Degree
  • 2+ years of academic and/or industry experience
  • Experience with histopathology techniques required, including tissue trimming, processing, embedding, slide cutting for H&E, special stains, and troubleshooting tissue/slide problems.
  • Experience in developing IHC or ISH assay for novel targets.
  • Strong written and oral communication skills are critical.
  • Ability to work well within a team and strong interpersonal skills.
  • Skilled in using word processing, spreadsheets, and PowerPoint presentation software.

Responsibilities

  • Responsible for tissue trimming (xenografts and PDX models), processing, embedding, and making microscopic slides for H&E and special stains.
  • Troubleshoot tissue/slide problems.
  • Develop and run IHC and ISH assays using Leica autostainer.
  • Scan and organize images.
  • Work closely with the MD pathologist to optimize assays.
  • Analyze and interpret experimental data.
  • Organize and present data/information for internal and external audiences.
  • Prepare and help transition IHC assays to CROs.
  • Maintain tissue bank, assign tissue ID, and log in tissue samples.
  • Communicate with vendors.
  • Share responsibilities in purchasing and laboratory supply inventory.
  • Share responsibilities in reporting instrument issues and help with equipment maintenance.
  • Document all work accurately using ELN and contribute to writing SOPs.

Benefits

  • Medical, pharmacy, dental, and vision care.
  • BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
  • 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
  • Flexible time off (unlimited, with manager approval) for US Exempt Employees.
  • 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees).
  • 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays for Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees.
  • Unlimited paid sick time (based on eligibility).
  • Up to 2 paid volunteer days per year (based on eligibility).
  • Summer hours flexibility (based on eligibility and role).
  • Leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs.
  • Annual Global Shutdown between Christmas and New Years Day.
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