Senior Associate Scientist, Oligonucleotides

Regeneron Pharmaceuticals•Tarrytown, GA

9d•$80,300 - $131,100•Onsite

About The Position

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an Associate Scientist/Senior Associate Scientist to join our Nucleic Acid Therapeutics group, supporting drug discovery and technology development in the field of oligonucleotide therapeutics such as siRNAs and antisense oligonucleotides. In this role, you will develop assays and execute high-throughput screenings of hundreds to thousands of candidate molecules, while collaborating with your team to advance oligonucleotide therapeutic programs. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Requirements

Bachelor's degree required
2+ years of industrial experience in a relevant field highly appreciated
Ability to independently execute and refine techniques with general guidance, multi-tasking across shifting priorities
Strong organizational and communication skills, with the ability to work well in a team

Nice To Haves

Master's degree preferred
experience with automated/semi-automated liquid handlers, KingFisher, and QuantStudio
knowledge of oligonucleotide chemistry and RNA biology

Responsibilities

Develop assays to enable high-throughput oligonucleotide library screenings
Execute high-throughput screening of hundreds to thousands of candidate molecules
Perform cell culture optimization, bDNA, RT-qPCR, cell line generation, and transfection optimization
Design probes and conduct compatibility tests, along with western blot analysis
Work with automated or semi-automated processes, including liquid handlers and instruments such as KingFisher and QuantStudio
Independently execute and refine techniques and technologies with general guidance
Multi-task and shift priorities based on communicated department needs
Thrive in a fast-paced environment, staying detail-oriented, organized, and eager to learn new techniques