Associate Scientist or Scientist in Translational Studies in Schizophrenia Models

St. Jude Children's Research Hospital•Memphis, TN

22d•$86,320 - $154,960•Onsite

About The Position

An Associate Scientist or Scientist position is available for a highly motivated individual seeking to transition from a postdoctoral role to a stable staff scientist position. The successful candidate will lead an independent research program focused on developing translational strategies to restore normal function in impaired neuronal circuits using mouse models of 22q11.2 deletion syndrome and 3q29 deletion syndrome. These rare neurodevelopmental disorders are associated with some of the highest known genetic risks for schizophrenia. The candidate also will benefit from an outstanding, highly collaborative work environment in which a diverse team of 15 researchers focuses efforts toward understanding the mechanisms of schizophrenia and psychotic behavior at the levels of neural circuits and individual neurons, synapses, and molecules. The laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including an integrated support structure for testing rodent behavior, producing genetically engineered animal models and 3-dimensional human brain organoids, in vivo and ex vivo imaging of cells, advanced image processing and analysis, single-cell profiling, and bioinformatics. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies.

Requirements

Bachelor's degree in relevant scientific area is required.
Associate Scientist Minimum Experience: 7 + years of research experience is required
Associate Scientist Minimum Experience: 5 + years of research experience is required with a Master’s degree
Associate Scientist Minimum Experience: 2 + years of research experience is required with a PHD
Scientist Minimum Experience: Eight (8) years of relevant work experience is required
Scientist Minimum Experience: Six (6) years of relevant work experience is required with a Master's degree
Scientist Minimum Experience: Three (3) years of relevant work experience is required with a PhD

Nice To Haves

Ph.D. in neuroscience or related fields
Strong background in molecular biology, ASO biochemistry, delivery, and validation assays
2-photon imaging of head-fixed animals
In vivo stereotaxic-guided injections of viruses
Strong communication skills
Experience leading and supporting research experiments preferred
Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred
Experience in guiding and training other laboratory personnel preferred
Proven performance in earlier role/comparable role

Responsibilities

Coordinates multiple aspects of research projects and carries out laboratory experiments utilizing various laboratory techniques, and determines whether additional or other tools or methods are required.
Provides input regarding research protocols and experiments. Sets up protocols and assists in developing new laboratory techniques as required.
Identifies experimental data pertinent to the analysis problem. Processes, organizes and summarizes data, reporting these experimental results as required. Monitors quality and integrity of recorded information and data.
May draft sections of research manuscripts.
Provides basic lab operation support to include equipment maintenance and purchasing. Monitors inventory levels and orders lab supplies as needed. Performs calibration of instruments and equipment. Troubleshoots instrument performance and equipment issues.
Instructs other staff in basic laboratory techniques and procedures.
Maintains regular and predictable attendance.
Performs other related duties as assigned in order to meet the goals of the department and institution.