Associate Scientist II (Contract), Analytical Development for Characterization

Vaxcyte•San Carlos, CA

7d•Onsite

About The Position

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. We are seeking a highly skilled and motivated Associate Scientist II (Contract) to join our Analytical Development team to support the characterization of drug substances, protein intermediates, and drug products using LC-MS and complementary analytical techniques. The ideal candidate would be central to implementing mass spectrometry-based workflows, interpreting complex data, and collaborating cross-functionally to advance our vaccine programs.

Requirements

BS in Chemistry, Analytical Chemistry, Biochemistry, or a related discipline, with minimum 2 years of relevant industry experience.
MS without experience; or equivalent work experience.
Hands-on experience utilizing mass spectrometry platforms, including hybrid Orbitraps, qTOFs, and triple quadrupoles.
Familiar with peptide mapping, and intact protein analysis workflows.
Excellent organizational skills, attention to detail, and documentation expertise.
Strong scientific curiosity and problem-solving abilities.
Effective communication and collaboration within cross-functional environments.
Ability to rapidly learn analytical workflows and technologies.

Nice To Haves

Experience using electronic lab notebook (ELN) systems is a plus
Scientific creativity and curiosity for applying new technologies to complex analytical challenges.

Responsibilities

Prepare samples and perform analyses per SOPs, including detailed data interpretation.
Independently execute analytical assignments with accuracy and efficiency.
Implement LC-MS workflows for proteins, conjugates, and other in-process molecules.
Operate, maintain, and troubleshoot Orbitrap, qTOF, and triple quadrupole mass spectrometers.
Conduct rigorous data analysis, interpret results, and present findings in team meetings.
Partner cross-functionally to develop analytical strategies and support their needs.
Maintain accurate documentation in an electronic lab notebook system.