Associate Scientist II, CMC Analytical Development

Arrowhead Pharmaceuticals•Verona, WI

1d•$65,000 - $78,000•Onsite

About The Position

Arrowhead Pharmaceuticals, Inc. is a commercial stage biopharmaceutical company focused on developing medicines for intractable diseases by silencing the genes that cause them. They utilize a portfolio of RNA chemistries and delivery methods to trigger RNA interference, leading to rapid, deep, and durable knockdown of target genes. Their therapies leverage the natural RNAi pathway for gene silencing. Arrowhead targets diseases with a genetic basis, often characterized by overproduction of disease-involved proteins. Their versatile RNAi technologies have the potential to address conditions in any therapeutic area and target diseases not addressable by small molecules and biologics. Arrowhead is a leader in bringing RNAi to diseases outside the liver, with a clinical pipeline including liver and lung targets and a promising preclinical pipeline. The company has corporate headquarters in Pasadena, CA, with R&D teams in Madison, WI & San Diego, CA, and a manufacturing facility in Verona, WI. Their employees are described as nimble, science-driven innovators collaborating to bring new therapies to patients.

Requirements

B.S in Chemistry (or related area of study)
At least 3 years of experience working in a chemistry laboratory setting
Familiar with analytical instrumentation, test methodology/validations, data acquisition systems, and cGMP policies and practices.
Ability to correctly analyze data/results and interpret outcome of experiments and to propose appropriate follow-up.
Strong attention to detail.
Works well with others and in a team environment
Flexible with changing priorities

Responsibilities

Know and adhere to cGMP policies and procedures and relevant SOPs
Work closely with team members to provide accurate analytical results in support of new and on-going projects
Work with supervision to meet project timelines and deliverables
Perform testing of samples to support batch release and stability studies
Perform portions of analytical techniques, such as HPLC, GC, FTIR, UV/Vis, LC/MS, KF, etc.
Assist with the design and initiation for development of analytical methods and improvement of existing ones to support all stages of drug development process
Handle, analyze and characterize chemicals, pharmaceuticals, and related organic molecules
Evaluate and interpret scientific data and provide the significance of such with supervision
Assist in the design and execution of non-routine experiments
Analyze data/results and interpret outcome of experiments and propose appropriate follow-up for straightforward studies
Compile data tables of results, certificate of analysis, and develop stability reports
Write analytical test methods and protocols
Calibrate, maintain, and troubleshoot simple and some complex analytical equipment
Other duties as assigned