Associate Scientist II, Analytical Development

Vaxcyte•San Carlos, CA

1d•Hybrid

About The Position

Vaxcyte is looking for an energetic and talented individual to join our Analytical Development team. Primary responsibility for the incumbent will be to support the developmental activities currently ongoing in the laboratory as assigned.

Requirements

BS in Chemistry, Analytical Chemistry preferred, Organic/Biochemistry considered, with 2–4 years of relevant lab experience
Ideal candidate will have a background in analytical chemistry principles and hands-on experience with modern analytical instrumentation commonly used in the analysis and characterization of drug candidates.
Candidates with other scientific disciplines may be considered based on relevant experience
Experience in chemical and biological assays such as colorimetric/fluorometric microplate assays and HPLC
Experience working with protein analysis – UV-Vis, CE, Bradford, etc.
Experience working with carbohydrate analysis and SEC-MALS a plus
Understanding of basic principles of analytical method development/validation/qualification concepts
Attention to detail and excellent skills in record keeping/documentation; critical thinking and ability to analyze data
Strong interpersonal skills: ability to communicate effectively both verbally and in written formats
Ability to work under supervision and independently in a fast-paced, cross-functional environment and collaborate effectively with other team members; eagerness and ability to learn and understand new concepts with ease
Other combinations of education and/or experience may be considered.

Nice To Haves

Experience working with carbohydrate analysis and SEC-MALS a plus
Experience with Chemstation
Experience with Protein Simple or PA-800 systems

Responsibilities

Maintain an organized and efficient laboratory workspace for the team
Primary responsibility to oversee the organization of chemical inventory, ensuring proper labelling, storage, and compliance with safety regulations
Assist in the organization and labelling of materials stored in freezers and refrigerators, ensuring easy access, proper storage and handling of samples and materials
Support daily lab operations, including sample inventory and sample shipment
Assist in the collection, labelling, and preparation of samples for analysis
Prepare reagents and solutions according to established protocols
Perform routine analytical testing by following established protocols, ensuring accurate execution of tests and documentation for proteins and carbohydrates including: Microplate assays including enzymatic assays and colorimetric assays such as Bradford, Lowry, etc. HPLC – Especially SEC and RP-HPLC with experience in Chemstation CE and iCIEF – Especially with Protein Simple or PA-800 systems
Keep accurate and detailed records of experiments
Maintain an accurate inventory of chemicals and reagents, tracking usage and expiration dates
Coordinate the ordering and restocking of laboratory supplies as needed
Collaborate within a team environment to support and further team objectives
Demonstrate flexibility and effectively complete assigned tasks with high quality and in a timely manner