Associate Scientist I, Technology Development

New York Genome Center•New York, NY
•$57,000 - $67,000•Onsite

About The Position

The Technology Development Lab at NYGC supports cutting-edge research through scientific collaboration, focusing on innovative single-cell and spatial genomic assay and tool development, optimization and application at scale. The Associate Scientist I will work with an expert team to develop and deploy state of the art genomics techniques. The ideal candidate will have a background in molecular biology and NGS-based platforms, with experience using single-cell and/or spatial technologies. Strong interpersonal and communication skills are required, as this role will work on an interdisciplinary team and actively collaborate across multiple internal and external groups. The ability to thrive in a fast-paced and shifting environment is essential.

Requirements

  • Bachelors’ degree in Molecular Biology, Biotechnology, Biochemistry, or related field required;
  • 2 years of experience in a molecular biology lab with at least 1+ years of demonstrated experience with next-generation sequencing library prep protocols and sequencing preferred;
  • Experience handling RNA and DNA, including extraction, quantification, visualization, modification, hybridization, and PCR is strongly preferred;
  • Solid knowledge of molecular biology equipment and related protocols (including RNA and DNA preparation, RNA and DNA quantification, hybridization, PCR, and bead-based solutions) highly preferred;
  • Experience with modern molecular biology tools including prior experience working with single-cell suspensions and/or tissue samples, such as cell sorting, nuclei isolation, tissue sectioning, staining, or imaging is a plus;
  • Experience working with single cell-based assays or spatial biology platforms is a plus;
  • Excellent laboratory and organizational skills including the ability to work independently and efficiently are essential;
  • Ability to multitask is a must, along with an orientation toward teamwork and cooperation;
  • Strong problem solving, excellent communication, and accurate bench skills required in addition to a passion for learning new things.

Responsibilities

  • Carry out procedures associated with DNA and RNA sequencing, including sample QC, library preparation and quantification;
  • Assist in performing assays on tissue and/or cell/nuclei suspensions using single cell and spatial methods, including snRNA-Seq, snMultiome, ASAP-Seq, DLP+, Visium HD, Xenium, etc.;
  • Contribute to the evaluation, development and troubleshooting of new and established methods by performing experiments and other tasks with guidance and supervision;
  • Ensure up-to-date standard operating procedures and edit as needed;
  • Collaborate closely with colleagues in the Technology Development and Production Lab teams, facilitating knowledge transfer and cross-functional coordination;
  • Maintain detailed, reliable, and timely laboratory records - tracking all work and issues in the appropriate databases/tracking sheets and/or electronic lab notebook;
  • Assist with regular maintenance of laboratory equipment and actively maintain laboratory cleanliness, organization, and safety procedures.

Benefits

  • Medical/Dental/Vision for employees & dependent(s)
  • Vacation, Holidays, Sick, and Other Leave, including a paid winter break
  • 401(k) match
  • Life Insurance
  • Flexible Spending Accounts
  • Employee Tuition Reimbursement
  • Employee Assistance Program
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