Associate Scientist I/II, Discovery Neuroscience

AbbVie•Cambridge, MA
•$58,656 - $99,000•Onsite

About The Position

We are seeking a highly motivated cell biologist to join our Discovery Neuroscience organization. This scientist will contribute to early discovery research efforts focused on identifying and advancing novel therapeutic approaches for Parkinson’s Disease and related neurodegenerative diseases. This laboratory-based role will support in vitro data generation, cell culture-based model development, evaluation of small molecule and biologic therapeutics, and execution of proof-of-concept studies in a collaborative discovery environment. The successful candidate will work closely with scientists across discovery biology and translational functions to generate high-quality data that inform program decisions.

Requirements

  • Associate Scientist I: Bachelor’s degree in Biology, Neuroscience, Pharmacology, Biochemistry, or a related scientific discipline (no additional experience) in an academic, biotech, or pharmaceutical setting.
  • Associate Scientist II: Bachelor’s degree with at least 3 years of experience in Biology, Neuroscience, Pharmacology, Biochemistry, or a related scientific discipline or MS (no additional experience)
  • Hands-on experience with high-content imaging, immunofluorescence, cell viability and reporter assays, ELISA, qPCR, and/or related cellular biology techniques.
  • Strong organizational skills, attention to detail, and commitment to high-quality data generation.
  • Effective written and verbal communication skills.
  • Ability to work independently and collaboratively in a fast-paced, team-oriented environment.

Nice To Haves

  • Experience with primary neuronal culture, iPSC-derived neurons and glia, and immortalized neuronal and glial cell lines.
  • Exposure to compound screening, assay development, troubleshooting, high-content image analysis, and mechanism of action studies in a discovery setting.
  • Experience analyzing and presenting experimental data.
  • Knowledge of neuroscience and/or neurodegenerative disease biology.
  • Familiarity with statistical analysis or data visualization tools.

Responsibilities

  • Design, execute, and interpret cellular experiments to support discovery neuroscience programs.
  • Collaborate effectively with cross-functional project teams to support program objectives and data interpretation.
  • Maintain and perform routine work with primary neuronal cultures, iPSC-derived neurons and glia, recombinant cell lines, and other neuroscience-relevant in vitro models.
  • Support compound testing, genetic knockdown/KO and overexpression studies, assay development, and proof-of-concept studies through careful execution of experimental workflows.
  • Contribute to assay optimization, troubleshooting, and implementation of new or modified in vitro methods.
  • Generate, organize, and analyze experimental data with a high degree of accuracy and reproducibility.
  • Maintain detailed and compliant experimental records, observations, and study documentation.
  • Adhere to applicable safety, quality, and data integrity standards.

Benefits

  • paid time off (vacation, holidays, sick)
  • medical/dental/vision insurance
  • 401(k)
  • short-term incentive programs
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