Associate Scientist I, CMC Analytical Development
About The Position
Arrowhead Pharmaceuticals, Inc. is a commercial stage biopharmaceutical company focused on developing medicines that treat intractable diseases by silencing the genes that cause them. The company utilizes a broad portfolio of RNA chemistries and efficient modes of delivery to trigger the RNA interference mechanism for rapid, deep, and durable knockdown of target genes. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. The company is dedicated to developing innovative drugs for diseases with a genetic basis, often characterized by the overproduction of disease-involved proteins. Their versatile RNAi technologies have the potential to address conditions in virtually any therapeutic area and pursue disease targets not addressable by small molecules and biologics. Arrowhead is a leader in applying RNAi to diseases outside the liver, with a clinical pipeline targeting liver and lung diseases and a promising preclinical pipeline. The Associate Scientist I will join the CMC Analytical Development team. This role is crucial for supporting analytical testing for drug substance and drug product development. The individual will be responsible for performing routine laboratory testing, assisting with analytical method development and qualification, and supporting release and stability testing for GLP toxicology studies and cGMP clinical trial materials. This position offers a valuable opportunity to learn analytical techniques in a collaborative laboratory setting while contributing to programs across various stages of drug development. The Associate Scientist I will work under the supervision of senior scientists and Analytical Development management.
Requirements
- Bachelor's degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related scientific discipline.
- 0-2 years of laboratory experience (industry, academic research, internships, or co-op experience considered).
- Basic understanding of analytical chemistry principles and laboratory techniques.
- Familiarity with analytical instrumentation through coursework or laboratory experience.
- Strong organizational skills and attention to detail.
- Excellent written and verbal communication skills.
- Ability to work effectively both independently and within a collaborative team environment.
- Comfortable managing multiple priorities in a fast-paced environment.
Nice To Haves
- Experience working in a cGMP or regulated laboratory environment.
- Hands-on experience with chromatography or other analytical instrumentation.
Responsibilities
- Follow cGMP guidelines, laboratory procedures, and applicable SOPs.
- Perform routine analytical testing to support batch release, stability studies, and development activities.
- Assist with analytical method development, qualification, and validation activities.
- Learn and perform analytical techniques including HPLC, GC, FTIR, UV/Vis, LC/MS, Karl Fischer, and other laboratory instrumentation.
- Prepare samples, reagents, and standards for laboratory testing.
- Accurately document experimental procedures and results in laboratory notebooks and electronic systems.
- Compile data, prepare certificates of analysis, and assist with stability reports.
- Analyze experimental data with guidance from senior team members.
- Calibrate, maintain, and perform basic troubleshooting of laboratory equipment.
- Collaborate with cross-functional teams to meet project timelines and deliverables.
- Maintain a clean, organized, and safe laboratory environment.
Benefits
- Competitive salaries
- Excellent benefit package
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
