Associate Scientist, Gene Engineering and Delivery
About The Position
The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes. The Gene Engineering and Delivery team in the Cell Therapy Thematic Research Center is seeking a highly motivated scientist to advance next-generation cancer immunotherapies through molecular design, viral vector engineering, and gene delivery innovation. This role will focus on designing, cloning, characterizing, and producing viral vector constructs that enable development of CAR T cell therapies. The ideal candidate brings molecular biology experience, hands-on cell culture experience, and a collaborative, problem-solving mindset in a fast-paced research environment.
Requirements
- Bachelor’s Degree
- 2+ years of academic and / or industry experience
- Strong molecular biology skills, including molecular assay development, molecular design and cloning of complex DNA constructs, PCR, RT-PCR, and mRNA and DNA preparation.
- Experience with tissue culture techniques, including transfection of mammalian cell lines and transduction of T cells.
- Excellent organization, time management, and problem-solving skills with strong attention to detail.
- Ability to design and execute experiments with some supervision
- Outstanding written, visual, and oral communication skills
Nice To Haves
- B.S./B.A. degree in a scientific discipline and 4+ years of hands-on experience in relevant field of research
Responsibilities
- Execute molecular design and cloning of complex DNA constructs for cell therapy applications.
- Demonstrate competency in mammalian cell culture, transfection, and transduction of primary T cells.
- Develop molecular engineering designs and assays that support gene delivery and viral vector characterization.
- Produce viral vectors to enable gene delivery workflows and experimental evaluation.
- Design and clone DNA constructs to support CAR T cell therapy development.
- Culture mammalian cell lines for viral vector production, assessment, and gene delivery applications.
- Set up and run molecular characterization and cellular assays to evaluate viral vector performance.
- Develop new molecular and viral vector characterization assays.
- Execute viral vector production and characterization protocols.
- Collaborate with team members to assess the technical feasibility of novel gene delivery methods.
- Process and analyze data, review results, and communicate conclusions clearly.
- Maintain accurate, detailed electronic laboratory notebook records and supporting documentation.
- Summarize and present data in group meetings and written reports.
- Work cross-functionally to execute and improve experiments and assay performance.
Benefits
- Medical, pharmacy, dental, and vision care.
- Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
- 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
- Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
- Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
- Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
- All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
High school or GED
