Associate Scientist, Analytical Development and Quality Control

Flagship Pioneering, Inc.•Cambridge, MA

1d•$96,000 - $126,500

About The Position

Serif Biomedicines is seeking a highly motivated and skilled candidate for the role of Associate Scientist on the Analytical Development and Quality Control team. This candidate will contribute to building efficient systems for testing samples and delivering data, as well as method optimization and qualification to support the characterization of novel nucleic acid therapeutics and LNP delivery vehicles. The ideal candidate enjoys hands-on laboratory benchwork, mentoring other team members, and brings scientific rigor and intellectual curiosity to their role. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment as part of a highly collaborative and rapidly growing team.

Requirements

B.S. degree with 8+ years or M.S. degree with 6+ years of relevant industry experience in Chemistry, Biochemical Engineering, Biochemistry, Molecular Biology, Chemical Engineering, Biotechnology or related field.
Technical expertise in HPLC separations, LC-MS, plate-based assays (e.g. ELISA, qPCR/dPCR, residual protein).
Ability to design, independently execute, and troubleshoot experiments.
Strong communication and organization skills.
Good working knowledge of Benchling, MS Office, JMP, GraphPad, Empower, Chromeleon.
Demonstrates attention to detail, meticulous record keeping and personal organization.
Ability to analyze, compile, and present experimental data in oral presentations as well as in technical reports.
Strong technical writing skills to support method SOPs, protocols, and reports.

Nice To Haves

Prior hands-on experience working with mRNA/DNA cargo and LNP products is highly desired.

Responsibilities

Work with the team to drive advancement of platform development and play a vital role in shaping our analytical capabilities.
Execute platform goals with tenacity and agility through benchwork.
Setup, maintain, and optimize a system for efficient sample testing and data delivery.
Ensure robustness of generated data through tracking historical data.
Execute experimental studies to optimize specificity, sensitivity, precision, accuracy, and/or linearity of analytical methods.
Analyze, troubleshoot, and communicate experimental findings clearly and succinctly in oral, written, and visual formats.
Troubleshoot assay development and instrument operation issues as they arise.
Run assays on samples generated during platform development studies.
Maintain inventory of nucleic acid cargo and deliver materials supporting development and formulation activities.
Document lab activities in detailed protocols and reports in an electronic lab notebook (Benchling).
Compose and revise SOPs and train team members on new assays.
Present experimental results and updates to internal teams.
Assist with general laboratory tasks as needed to ensure efficient operations.
Work independently and collaboratively in a multidisciplinary team environment.