Associate Principal Scientist - Process Engineer
About The Position
AstraZeneca is a global, science-led biopharmaceutical company. Pharmaceutical Technology & Development (PT&D) is responsible for turning brilliant science into real medicines, covering the entire value chain from early toxicology and clinical supplies to technology that enables robust commercial manufacture. Global Product Development (GPD) leads the late-stage design and development of drug products. This role involves collaborating in multidisciplinary teams with engineers and pharmaceutical scientists to advance life-changing medicines for patients. The opportunity is for an Associate Principal Scientist in Process Engineering with experience in solid dosage product development (tablets, capsules) to grow the engineering capability within Global Product Development. As a senior scientist, you will lead the process engineering aspects of late-stage development projects for oral solid dosage forms, including Continuous Direct Compression. You will be a key member of a multidisciplinary team, contributing to overall product development, designing and executing lab and pilot plant work, and implementing in silico tools. The ideal candidate is a problem solver and team player who thrives under pressure and is passionate about developing robust manufacturing processes.
Requirements
- Bachelors Degree in Related Discipline (e.g - Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences) with 5 - 10 years of relevant industrial experience.
- Experience in oral solid dose development.
- Experience in late-stage product development, technology transfer, scale-up and process validation.
- Fundamental understanding of control strategy and risk management.
- Basic understanding of predictive science, artificial intelligence, modelling and simulation.
- Excellent communication and collaboration skills
Nice To Haves
- Masters or PhD in Life Sciences (e.g. - Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences).
- Experience with a range of unit operations e.g. continuous manufacturing, granulation, compression, coating.
- Experience with regulatory authoring and defence.
- Experience with CMOs/CROs and outsourced development.
Responsibilities
- Lead engineering input for the design and development of robust manufacturing processes for oral solid dosage forms.
- Plan and execute lab-scale experiments to facilitate project decisions.
- Shape the scientific and technical direction of product development activities through process understanding and control.
- Define and optimize critical process parameters (CPPs) and integrate them into control strategies.
- Lead or contribute to technology transfer, risk assessment, process validation and scale-up.
- Apply modelling, simulation, digital twins and predictive tools to enhance process understanding.
- Solve key technical challenges with direct impact on current project delivery.
- Drive a culture of creativity, innovation and scientific excellence.
- Contribute to integrated drug product development plans within a multidisciplinary team.
Benefits
- Qualified retirement program [401(k) plan]
- Paid vacation and holidays
- Paid leaves
- Health benefits including medical, prescription drug, dental, and vision coverage
- Flexible employee benefits fund
- Holiday purchase
- Flexible time off
- Pension contributions
- Share Save Plans
- Performance recognition scheme
- Competitive, generous remuneration package
- Short-term incentive bonus opportunity
- Eligibility to participate in our equity-based long-term incentive program (salaried roles)
- Retirement contribution (hourly roles)
- Commission payment eligibility (sales roles)
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Number of Employees
5,001-10,000 employees
