Associate, Membrane Protein Biochemistry

AmgenSouth San Francisco, CA
Onsite

About The Position

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Associate, Membrane Protein Biochemistry What you will do Let’s do this. Let’s change the world. In this vital role you will design strategies for recombinant production of polytopic membrane protein (MP) targets and purify MPs into stable formulations with detailed analytical characterization. This role will also include opportunities to develop capabilities that increase the success rates of large-molecule and small-molecule therapeutic discovery programs. This is an onsite laboratory position at our South San Francisco site.

Requirements

  • Bachelor’s degree OR Associate’s degree and 2 years of relevant laboratory experience OR High school diploma / GED and 4 years of relevant laboratory experience

Nice To Haves

  • Ph.D. plus 0-2 years of relevant postdoctoral experience
  • Demonstration of independent design, execution, and interpretation of experiments and results, as exemplified by a solid publication record with first-author publication(s)
  • Proven expertise with ÄKTA systems and analytical methods for membrane protein characterization using quality-focused analytical methods such as HPLC/UPLC (SEC, fSEC), spectroscopy, or mass spectrometry.
  • Proven expertise in structural biology or dissection of MP molecular pharmacology is a plus
  • Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams in a fast-paced environment

Responsibilities

  • Independently devise and implement state-of-the-art membrane protein production strategies through conducting laboratory experiments with rigorous documentation and emphasis on quality of deliverables
  • Analyze and interpret scientific data with the intent to communicate results to audiences with diverse scientific backgrounds
  • Collaborate with other scientists to plan methodological approaches, necessary resources, timelines, and milestones to drive defined projects forward
  • Keeping current in membrane protein expertise to advise supervisors and colleagues on future membrane protein technology development strategies

Benefits

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible.
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