Associate Manufacturing Scientist I (2nd shift)
About The Position
Arrowhead Pharmaceuticals, Inc. is a commercial stage biopharmaceutical company focused on developing medicines that treat intractable diseases by silencing the genes that cause them. The company utilizes a broad portfolio of RNA chemistries and efficient modes of delivery to trigger the RNA interference mechanism for rapid, deep, and durable knockdown of target genes. Arrowhead's RNAi-based therapeutics leverage the natural pathway of gene silencing to inhibit the expression of specific genes. The company is dedicated to developing innovative drugs for diseases with a genetic basis, often characterized by the overproduction of disease-involved proteins. Arrowhead's technologies enable the potential to address conditions in virtually any therapeutic area and pursue disease targets not addressable by small molecules and biologics. The company is a leader in bringing RNAi to address diseases outside of the liver, with a clinical pipeline targeting diseases in the liver and lung, and a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters are in Pasadena, CA, with research and development teams in Madison, WI & San Diego, CA, and a state-of-the-art manufacturing facility in Verona, WI. The employees are described as nimble, science-driven innovators collaborating to bring new therapies to patients.
Requirements
- Bachelor's degree in Chemistry, Biochemistry, Biology, Chemical Engineering, or another scientific discipline or equivalent relevant manufacturing experience.
- 0–2 years of laboratory or manufacturing experience in biotechnology, pharmaceutical, chemical, or related industries.
- Ability to follow detailed written procedures and maintain accurate documentation.
- Strong attention to detail and commitment to quality.
- Ability to work independently while collaborating effectively within a team.
- Strong verbal and written communication skills.
- Demonstrated ability to prioritize work in a fast-paced manufacturing environment.
Nice To Haves
- Experience working in a GMP-regulated manufacturing or laboratory environment.
- Hands-on experience with chromatography, filtration, purification, or analytical instrumentation such as LC-MS.
- Familiarity with manufacturing documentation, batch records, or ERP systems.
Responsibilities
- Follow batch records, SOPs, and work instructions to detail
- Document all operations in batch records and logbooks
- Comply with GMP protocols
- Operate large scale oligonucleotide manufacturing equipment (i.e. oligonucleotide synthesizer, purification skid, tangential flow filtration system, lyophilizer, ChemGlass reactors, pH/conductivity meters, peristaltic pumps, etc.)
- Assist other chemists within the Manufacturing group during synthesis and purification of oligonucleotides including Reagent solution preparation, Mobile phase preparation, Column Packing, Fraction collection
- Perform oligonucleotide/intermediate analysis via LCMS
- Communicate with cross-functional groups such as Process Development, Analytical Development, Quality Control, Quality Assurance, etc.
- Maintain a clean work space
- Maintain safety by wearing required personal protective equipment
- Track and update raw material usage in D365 ERP software
- Act as production campaign lead
- Assist with new personnel training
Benefits
- competitive salaries
- excellent benefit package
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
