Associate Director, Translational Medicine, Neuroscience
About The Position
Translational Medicine at BMS is a department within the Research organization that facilitates the transition of drug candidates from early to late-stage clinical development, their approval and life cycle management. Early-stage translational development activities enable rational determination of dose-schedule and responsive patient populations, based on deep understanding of drug mechanism of action and disease segments. Late-stage translational development activities build upon the early work, additionally exploring mechanisms of response/non-response, rational drug combinations and product differentiation. The late-stage translational development function is responsible for the development of translational strategies to support the development, and maximize the potential, of BMS’s therapies post-clinical proof-of-concept, including registrations and life-cycle management. Translational disease strategies in Alzheimer’s /Neurological Diseases are derived from long term investments in developing data and deep expertise in disease biology, neuroinflammation and patient segments to assist science driven strategies for the development of the neuroscience pipeline.
Requirements
- PhD degree in a neuroscience-related field
- Minimum of 8 years post-PhD experience, with demonstrated scientific leadership in integrating, analyzing, and interpreting multimodal biological data in an academic and/or industry setting.
- Strong background in neuroscience with focus on Alzheimer’s disease, human genetics/genomics, molecular and cellular biology is required. Knowledge in immunology is a plus.
- Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity.
- Strong team player with the ability to work in cross-functional teams. Excellent communication and collaboration skills.
- Strong track record of high-quality scientific publications in relevant fields
Nice To Haves
- Prior experience with clinical trials preferred but not essential
Responsibilities
- Develops and executes translational disease strategy in Alzheimer’s /Neurological disease areas with deep disease expertise
- Leads and oversees execution of disease strategy including but not limited to various aspects of patient selection strategies
- Serves as scientific expert in generating novel hypotheses for targetable biologies based on novel discoveries integrating disease work with literature and deep expertise in neuroscience
- Manages cross functional disease project teams with key interfaces in IT, bioinformatics, data sci, stats, external collaborators, contractors, other disease strategy leads and asset leads
- Maintains relationship with translational clinicians for identifying new opportunities and for gaining disease insight
- Identifies needs, gaps and translational disease questions and applies knowledge across all assets in BMS portfolio in neuroscience area
- Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
- Collaborate and guide bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, epigenetics, proteomics, immune profile and single cell data in order to support drug discovery and development in Alzheimer’s /Neurological Diseases.
- Manage relationships with key internal stakeholders including regulatory, clinical and commercial and scientific communications and external collaborators to develop translational analysis plans and timelines, communicate analysis results.
- Represent the Neurology Translational Medicine function at various internal meetings and provide domain knowledge and disease expertise to cross-functional teams.
- Direct and support publications in high quality scientific, technical or medical journals.
Benefits
- wellbeing support
- retirement and financial protection benefits
- insurance offerings (medical, dental, vision, life and disability)
- Flexible Time Off (FTO)
- 11 paid company holidays each year
- 160 hours of paid vacation annually
- 3 optional holidays
- paid sick leave
- up to two paid volunteer days per year
- summer hours flexibility
- leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs
- annual Global Shutdown between Christmas Day and New Year's Day
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What This Job Offers
Job Type
Full-time
Career Level
Director
Education Level
Ph.D. or professional degree
