Associate Director/Senior Manager, Health Economics & Outcomes Research-Organ Health

Natera

2d•$191,800 - $239,800•Remote

About The Position

We are seeking a strategic, analytical, and highly collaborative leader to serve as our Associate Director/Senior Manager of Health Economics & Outcomes Research (HEOR) Organ Health. In this high-impact role, you will lead the development and execution of health economic and outcomes evidence demonstrating the clinical and economic value of Natera’s precision molecular diagnostic technologies across chronic kidney disease (CKD), transplant medicine and emerging indications. You will develop health economic models, generate real-world and clinical-trial evidence, lead HEOR publication initiatives, and translate complex clinical and economic data into compelling evidence supporting market access, reimbursement, payer adoption, clinical adoption, and commercialization. Working across Medical Affairs, Clinical Development, Biostatistics, Market Access, Commercial, Marketing, Regulatory, and Business Development, you will help integrate HEOR evidence throughout the product lifecycle—from clinical development and evidence generation through publication, reimbursement, and payer adoption. This is a strategic role for an experienced HEOR professional who combines strong technical capabilities with scientific communication, business acumen, and the ability to influence cross-functional evidence strategy.

Requirements

Advanced degree (PhD, PharmD, MD, DrPH, or Master's degree) in Health Economics, Outcomes Research, Epidemiology, Public Health, Biostatistics, Pharmacy, Health Services Research, or a related discipline.
5–10+ years of HEOR experience within biotechnology, pharmaceuticals, diagnostics, medical devices, consulting, academia, or a related healthcare environment.
Demonstrated experience developing and applying health economic models and conducting outcomes research using clinical-trial and/or real-world datasets.
Experience supporting payer evidence generation, reimbursement strategy, value dossiers, market access initiatives, and scientific publications.

Nice To Haves

Experience with precision medicine, molecular diagnostics, companion diagnostics, ctDNA, molecular residual disease (MRD), donor-derived cell-free DNA (dd-cfDNA), next-generation sequencing, biomarker-guided treatment strategies, or Organ Health diagnostics is highly desirable.
Familiarity with advanced economic and analytical tools such as Microsoft Excel, TreeAge Pro, R, SAS, STATA, Python, SQL, Tableau/Power BI, and statistical analysis software is preferred.
Understanding of U.S. and international reimbursement environments and major HTA frameworks, including ICER, NICE, CADTH, PBAC, IQWiG, and Japanese reimbursement processes.

Responsibilities

Lead the development, validation, and application of health economic models, including budget impact, cost-effectiveness, cost-utility, cost-consequence, ROI, decision-tree, Markov/state-transition, partitioned-survival, and other economic models.
Develop scenario and sensitivity analyses that quantify the clinical and economic value of precision diagnostics across different payer and healthcare-system perspectives.
Partner with Clinical Development, Medical Affairs, Biostatistics, and other cross-functional teams to integrate HEOR objectives into prospective clinical studies, including healthcare resource utilization, economic endpoints, patient-reported outcomes, quality-of-life measures, cost-data collection, and real-world evidence strategies.
Ensure evidence-generation plans anticipate future payer, reimbursement, and HTA requirements.
Analyze clinical-trial, observational, and real-world datasets to evaluate healthcare resource utilization, cost of care, treatment pathways, diagnostic utilization, clinical utility, comparative effectiveness, patient outcomes, survival, budget impact, and quality-adjusted life years.
Translate findings into actionable evidence supporting clinical, payer, and business decisions.
Lead HEOR publication strategy and development of peer-reviewed manuscripts, scientific abstracts, conference posters, oral presentations, white papers, and technical reports.
Coordinate publication plans and timelines with investigators, key opinion leaders, academic collaborators, and external research partners to ensure evidence generation is aligned with strategic business priorities.
Partner with Market Access, Medical Affairs, Marketing, and Commercial teams to translate HEOR evidence into payer value propositions, budget impact summaries, value dossiers, reimbursement materials, health economic briefs, health-system value calculators, account-specific economic tools, and other evidence-based value communications.
Develop and adapt health economic evidence and payer models for the U.S. and international markets, including Europe, Japan, Canada, Australia, and other priority geographies.
Support reimbursement submissions and evidence strategies aligned with HTA and payer requirements across healthcare systems.
Serve as a strategic HEOR partner across Medical Affairs, Clinical Development, Biostatistics, Market Access, Commercial, Marketing, Regulatory, and Business Development.
Collaborate with external consultants, academic investigators, KOLs, and research partners to execute high-quality evidence-generation initiatives.