Associate Director Quantitative Pharmacology

Regeneron Pharmaceuticals•Warren, MA

10d•Hybrid

About The Position

Build Our Future Together We are seeking a highly motivated Associate Director to join the Quantitative Pharmacology (QP) group. The Associate Director will lead model-informed drug development strategies supporting one or more therapeutic areas across modalities including antibodies, siRNA, and gene therapies. This role combines scientific depth with cross-functional leadership to inform dose selection, trial design, and regulatory strategy from early development through submission.

Requirements

PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field with 7+ years of post-doctoral or industry experience; or MS with 9+ years of relevant experience.
Demonstrated expertise in population PK/PD, exposure–response, or mechanistic modeling (systems biology, or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R.
Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).
Hands-on experience with a broad range of quantitative and computational tools and a strong publication record.
Exceptional communication and interpersonal skills, with the ability to influence and partner effectively across technical and non-technical teams.

Responsibilities

Proactively identify and provide significant Pharmacometrics contribution potentially of a complex nature for research and development programs that address strategically important program needs, and that represent scientific advancements of one or more programs and/or aptly address significant regulatory hurdles.
Contribute to the overall strategic program development and is able to communicate complex Pharmacometrics strategies and results in an influential manner to the development team.
Independently design and conduct or otherwise oversee the development of PMx analysis plans and applies standardized or advanced scientific techniques to conduct PK, PD, and/or other types of quantitative analyses.
Is responsible for the preparation and timely delivery of accurate and well-articulated nonclinical or clinical study reports and regulatory submission documents as appropriate.