Associate Director Quantitative Pharmacology

Regeneron Pharmaceuticals

2d • $176,100 - $287,300 • Onsite

About The Position

We are seeking a highly motivated Associate Director to join the Quantitative Pharmacology (QP) group. The Associate Director will lead model-informed drug development strategies supporting one or more therapeutic areas across modalities including antibodies, siRNA, and gene therapies. This role combines scientific depth with cross-functional leadership to inform dose selection, trial design, and regulatory strategy from early development through submission.

Requirements

• PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field with 6+ years of post-doctoral or industry experience; or MS with 9+ years of relevant experience.
• Demonstrated expertise in population PK/PD, exposure–response, or mechanistic modeling (systems biology, or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R.
• Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).
• Hands-on experience with a broad range of quantitative and computational tools and a strong publication record.
• Exceptional communication and interpersonal skills, with the ability to influence and partner effectively across technical and non-technical teams.

Nice To Haves

• Want to make a visible impact on the organization by driving data-driven decisions that shape clinical and regulatory strategy.
• Thrive in multi-disciplinary environments, bridging discovery, clinical, and commercial teams.
• Communicate complex modeling concepts clearly and persuasively to diverse stakeholders.
• Have strong collaboration and leadership skills, influencing cross-functional teams without formal authority.
• Can independently design, execute, and oversee multiple modeling workstreams simultaneously.

Responsibilities

• Driving model-informed development (MIDD) and pharmacometrics strategies in partnership with Clinical Pharmacology, Biostatistics, Clinical and Translational teams to support regulatory and clinical decision-making.
• Leading the QP evaluation of one or more assets, accountable for timely delivery of population PK/PD, exposure–response, and translational modeling analyses.
• Representing QP at program and governance meetings, communicating quantitative insights clearly to non-modeling audiences.
• Contributing to regulatory interactions and authoring key components of regulatory documents related to QP (e.g., IB, briefing books, etc.).
• Mentoring and developing junior scientists and fostering a culture of scientific rigor and collaboration.
• Identifying and implementing process improvements, new modeling approaches, and innovative quantitative tools to enhance efficiency and impact.
• Ensuring analyses and documentation are of the highest scientific quality and regulatory compliance.

Benefits

• health and wellness programs (including medical, dental, vision, life, and disability insurance)
• fitness centers
• 401(k) company match
• family support benefits
• equity awards
• annual bonuses
• paid time off
• paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree