Associate Director Neuroscience & Ophthalmology Genetics

Regeneron Pharmaceuticals • Tarrytown, GA

19h • Onsite

About The Position

We are seeking a Physician Scientist to join our Neuroscience and Ophthalmology Therapeutic Area Genetics (TAG) team. We see this role as a subject matter authority in the translation of human genetic evidence into actionable insights in neurological, psychiatric, ophthalmological, hearing- and aging-related diseases. You will work closely with other teams in the Regeneron Genetics Center and Regeneron at large and be primarily responsible for designing, contributing to the execution of, and interpreting large and complex human genetic studies in the therapeutic areas. We hope you are excited by the opportunity to play a role in the development and implementation of innovative translational sciences and identify new therapeutic targets through genetic approaches.

Requirements

• Demonstrated ability to design and lead human genetics studies delivering medically relevant findings in a team-based environment.
• Use medical knowledge to define relevant phenotypes for genetic association studies and to formulate innovative and important research questions.
• Familiarity with clinical genetics concepts and various genetic models of disease.
• Experience leading complex human genetics research endeavors, knowledge of different study designs and analyses including GWAS, exome, or genome sequencing in cohort, case-control, or family-based studies, and ability to integrate different data resources to translate initial findings.
• Interest in understanding the genetic basis and causes of Neurological, Psychiatric, Ophthalmological, Hearing- and Aging-related diseases and translating this knowledge into therapeutic insights.
• MD or MD/Ph.D. with a strong background in and knowledge of human genetics or genetic epidemiology.

Nice To Haves

• Previous experience with phenotypes related to neurological, psychiatric, ophthalmological, hearing- and aging-related diseases.
• An MD/Ph.D. with training and experience in translational human genetics, genetic epidemiology (or related disciplines), and strong quantitative skills.
• Familiarity with the applications of statistical genetics to gain medically actionable insights including polygenic risk scores, quantitative traits analyses, and Mendelian randomization.
• Familiarity with command-line interface, programming languages, and statistical software (eg. Python, R).
• Experience with the use of genetics in combination with other “omics” technologies (eg. epigenetics, proteomics, RNA-seq).

Responsibilities

• Applying human genetics to target discovery, selecting indications for drug programs, and identifying subgroups of patients who are more likely to respond to treatment through genetic analyses.
• Working with a multidisciplinary genetics team consisting of human genetics scientists, bioinformaticians, statistical geneticists, and other team members to design, execute, and interpret genetics studies in ophthalmology.
• Working in close collaboration with other Therapeutic Area Genetics team members and forming a strong partnership with Genome Informatics, Analytical Genomics, Clinical Informatics, and other RGC teams to deliver on complex, top-quality scientific endeavors in these Therapeutic Areas.
• Generating, summarizing, and presenting results in internal and external meetings to a variety of audiences.
• Leading or contributing to the writing of scientific reports and publications.
• Representing the TAG team in cross-functional initiatives within RGC and Regeneron.
• Collaborating with external industry and academic partners in scientific consortia.

Benefits

• Health and wellness programs (including medical, dental, vision, life, and disability insurance)
• Fitness centers
• 401(k) company match
• Family support benefits
• Equity awards
• Annual bonuses
• Paid time off
• Paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees