Associate Director/Director, Non-Clinical and Translational Research

UroGen Pharma, Inc•,

8d•Onsite

About The Position

UroGen is seeking an accomplished, collaborative scientist to lead the development and execution of nonclinical and translational research activities supporting oncology programs. The role may be filled at the Associate Director or Director level, depending on the candidate’s experience and qualifications. As the organization grows, there may be an opportunity to establish internal laboratory capabilities and lead a high-performing research team. The position requires regular in-person work in Philadelphia.

Requirements

Ph.D. in cell biology, immunology, virology, or a related discipline.
Expertise in tumor immunology and/or virology.
At least five years of relevant biotechnology or pharmaceutical industry experience.
Experience leading nonclinical and/or translational aspects of cancer drug discovery or development programs.
Direct experience drafting nonclinical sections of IND submissions.
Demonstrated success managing outsourced research relationships.
Strong understanding of nonclinical studies and regulatory requirements needed to advance programs into and through clinical development.
Ability to integrate multidisciplinary data into clear, evidence-based recommendations.
Strong scientific judgment, collaboration, and written and verbal communication skills.
Ability and willingness to work regularly in person in Philadelphia.

Nice To Haves

Experience designing and characterizing novel oncolytic viruses and/or other novel therapeutics.
Experience building laboratory capabilities.

Responsibilities

Lead nonclinical and translational research activities aligned with program, clinical development, and regulatory objectives.
Design and oversee in vitro and in vivo studies evaluating mechanism of action, pharmacology, efficacy, and/or biodistribution.
Select and manage vendors and consultants, including study design, protocol development, data review, troubleshooting, and final reports.
Lead preparation of nonclinical sections of IND submissions and other regulatory documents, and partner with nonclinical safety/toxicology to integrate findings.
Evaluate clinical pharmacodynamic and predictive biomarker data to assess biological activity, inform dosing regimen and/or patient selection, and guide program decisions.
Support scientific due diligence and evaluation of licensing, partnering, and other business development opportunities.