Associate Director, Clinical Operations Site Engagement Lead

CSL • Waltham, MA

1d • $186,000 - $220,000 • Hybrid

About The Position

The Associate Director, Site Engagement Lead is responsible for developing and executing a strategic, cross-functional engagement approach for assigned clinical programs and studies. The role serves as a voice for clinical sites within CSL, ensuring that site perspectives, operational realities, and external intelligence are translated into actionable insights that improve study feasibility, site selection, recruitment, retention, study execution, and the overall site experience. Working in close collaboration with Clinical Development, Clinical Trial Management, Site Management, Feasibility, Start-up, Medical Affairs, and other functions, the Associate Director, Site Engagement Lead builds trusted relationships with investigators and institutions while driving internal alignment, informed decision-making, and continuous improvement. The role requires an individual who can operate strategically while remaining close to operational realities, influence without direct authority, constructively challenge established approaches, and translate insights into meaningful and measurable outcomes.

Requirements

• Advanced degree in life sciences, pharmacy, medicine, or a related health/scientific discipline. PhD, PharmD, MD, or equivalent advanced degree preferred.
• 10+ years of relevant experience in clinical research, clinical operations, medical affairs, site engagement, or a related discipline, with significant experience in global clinical development.
• Demonstrated experience working across the clinical trial lifecycle, with a strong understanding of the operational realities of clinical trial delivery.
• Significant experience working in a sponsor or CRO environment, ideally including experience within a pharmaceutical or biotechnology sponsor organization.
• Experience working internationally and across multiple geographies and cultures.
• Demonstrated ability to lead cross-functional teams and drive outcomes through influence rather than direct authority.
• Strong ability to analyze complex qualitative and quantitative information, identify meaningful patterns and insights, and translate them into clear recommendations for senior stakeholders.
• Excellent communication, presentation, relationship-building, and stakeholder-management skills.
• Strong proficiency in PowerPoint and Excel.
• Willingness and ability to travel regionally and internationally, up to approximately 30%

Nice To Haves

• International Clinical Trial Management experience, ideally 4+ years
• Experience in a fully outsourced or hybrid clinical trial operating model
• Previous CRA experience
• Experience in Clinical Development, Clinical Operations, Medical Affairs, MSL, Feasibility, Site Management, or related functions
• Experience with Power BI, Smartsheet, or similar data visualization, analytics, and workflow-management tools
• Experience engaging with investigators, academic institutions, research networks, or other clinical research stakeholders at a strategic level

Responsibilities

• Develop, own, and continuously refine the engagement strategy for assigned programs and studies, aligned with program objectives and the broader CSL clinical development strategy.
• Establish and lead a cross-functional, program/study-specific Engagement Team, aligning stakeholders on engagement priorities, objectives, activities, and expected outcomes.
• Develop and drive proactive, purposeful, and actionable engagement plans across the full study lifecycle, from protocol concept and feasibility through study execution and close-out.
• Serve as the strategic voice of the site within CSL, bringing site perspectives, operational realities, and external intelligence into study and program decision-making.
• Translate site feedback, operational data, and external intelligence into actionable insights and recommendations that inform feasibility, site selection, recruitment, retention, study execution, and site experience.
• Use site intelligence to identify risks, barriers, and opportunities early, and constructively challenge assumptions, processes, and approaches where they may affect feasibility, site burden, quality, timelines, or study delivery.
• Align and influence stakeholders across functions and geographies to ensure site engagement priorities are embedded in study decisions and translated into action.
• Ensure site engagement is coordinated and consistent across CSL functions, providing sites with a seamless experience throughout the study lifecycle.
• Identify and drive opportunities to simplify processes, reduce unnecessary site burden, strengthen communication, and improve quality, efficiency, timelines, and cost.
• Capture and share lessons learned and site insights to strengthen future study planning, execution, and engagement approaches.
• Build and maintain strong, trusted relationships with key institutions, investigators, and partner sites, positioning CSL as a responsive, collaborative, and valued partner.
• Develop a deep understanding of investigator and site needs, capabilities, challenges, and expectations across therapeutic areas, geographies, and healthcare systems.
• Engage proactively with sites to understand emerging operational trends, barriers, opportunities, and external developments that may influence clinical trial delivery.
• Establish effective and sustainable feedback mechanisms and communication pathways between sites and CSL, ensuring relevant insights are captured, connected to the right stakeholders, and acted upon.
• Use external relationships and site intelligence to identify opportunities for improving study feasibility, site experience, recruitment, retention, and execution.
• Champion the site perspective while balancing the needs of investigators, study teams, patients, and the broader business to deliver meaningful and sustainable outcomes.

Benefits

• Relocation and mobility assistance are not provided.
• In addition to base salary, total compensation for this role may also include incentive compensation and equity.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior