Associate Director, Clinical Data Management

Artiva Biotherapeutics•San Diego, CA

7d•$190,000 - $205,000

About The Position

Artiva Biotherapeutics is seeking an Associate Director, Clinical Data Management to lead and scale our CDM function as we advance our NK cell therapy pipeline. This is a senior leadership role that combines hands-on program oversight with organizational accountability and serves as the internal subject matter expert on all things data management. This role is responsible for managing end-to-end data management activities across one or more clinical studies. Reporting to the Director or Head of Clinical Development Operations, the AD will be a key partner to Clinical Operations, Biostatistics, Translational Sciences, and Regulatory Affairs — driving quality, timelines, and innovation across Artiva's clinical data infrastructure. This is an ideal opportunity for a seasoned CDM leader who is energized by the opportunity to shape a function from the ground up in a high-impact, mission-driven organization.

Requirements

10+ years of clinical data management experience in pharma, biotech, or CRO, with 5+ years in progressive leadership roles
Demonstrated experience managing and overseeing Data Management activities directly and through CRO/third-party service providers
Deep expertise in EDC systems (Medidata Rave preferred) and clinical data standards (CDISC CDASH/SDTM, ICH GCP E6(R3), 21 CFR Part 11)
Proven track record managing CRO and third-party DM vendor relationships across multiple concurrent studies
Strong cross-functional communication and stakeholder management skills; ability to influence without authority at all levels of an organization
Strong cross-functional communication and stakeholder management skills; ability to influence without authority at all levels of an organization
Experience supporting regulatory submissions (IND, NDA/BLA) and/or inspection readiness activities preferred
Bachelor's degree in life sciences, computer science, or related field; advanced degree a plus

Nice To Haves

Experience supporting regulatory submissions (IND, NDA/BLA) and/or inspection readiness activities
Advanced degree

Responsibilities

Execute Artiva's CDM strategy — including technology platforms, data standards, vendor governance, and quality frameworks — in alignment with overall Clinical Development objectives
Serve as the CDM functional representative on program teams and governance forums; partner with Clinical Operations, Biostatistics, Regulatory, and Translational Sciences to ensure integrated, inspection-ready data delivery
Drive departmental SOPs, working practices, and process improvement initiatives; ensure the CDM function is prepared for internal audits and regulatory inspections
Provide senior oversight of all CDM activities across assigned programs from study start-up through database lock, ensuring timely delivery of high-quality, clean, and complete data
Lead or oversee development and review of DM documents including CRFs, Data Management Plans, edit check specifications, Data Review Plans, and SAE reconciliation plans
Lead Artiva UAT strategy and execution for EDC builds; ensure UAT standards are maintained across the program
Manage and govern CRO and third-party vendor relationships for DM activities; oversee scope, quality, timelines, and budget; escalate and resolve issues proactively
Drive program-level DM timelines; maintain cross-study visibility of milestones, risks, and resource needs; report status to leadership
Coordinate and lead Artiva data quality reviews
Participate in regular study and project team meetings
Foster a culture of quality and continuous improvement
Champion CDISC standards adoption (CDASH, SDTM) and EDC best practices across the organization
Evaluate and implement tools and technologies that advance data quality, efficiency, and real-time data visibility (e.g., risk-based monitoring integration, data review automation)
Mentor and develop CDM staff at all levels.