Asst Research Scientist/Engin - Li Lab

University of Iowa•Iowa City, IA

About The Position

The Department of Pathology seeks an Assistant Research Scientist to investigate how A-FABP and E-FABP regulate cell metabolism and intracellular signaling pathways in cells from disease models including obesity, cancer, and psoriasis. The position involves designing and carrying out assigned research projects and obtaining high-quality data for each study. Responsibilities also include managing laboratory protocols and training and collaborating with laboratory personnel, including students, postdoctoral fellows, and technicians. The position is 100% time. The Department of Pathology is part of UI Health Care, a comprehensive health sciences center serving Iowa and the region, as well as patients referred from across the United States and overseas. The department provides clinical care and participates in educational programs for medical students, clinical laboratory scientists, and biomedical scientists. Applicants must upload a resume and cover letter and mark each as a “Relevant File” in their submission to be considered for an interview. Job openings are posted for at least seven calendar days and may be removed and filled any time after that period. Successful candidates will undergo criminal background checks and credential and education verification. Up to five professional references may be requested later in the recruitment process.

Requirements

Ph.D. in Immunology or a related field.
At least 1 year of postdoctoral experience in Immunology or a cancer-related field.
Ability to independently design, optimize, and perform experiments and establish protocols to address scientific questions.
Record of publications in peer-reviewed journals.
Evidence of establishing a national presence through talks, abstract presentations, and/or participation in professional meetings.
Excellent communication skills and a positive, collaborative approach to teamwork.

Nice To Haves

At least 3 years of postdoctoral experience in Immunology or a cancer-related field.
Experience developing mouse models involving high-fat diet or tumor implantation and compliance with IACUC regulations.
High proficiency in multicolor flow cytometry to identify immune cells, including T cells and macrophages.
Proficiency in standard molecular biological and immunological techniques.

Responsibilities

Design and perform assigned research projects and obtain high-quality data.
Manage laboratory protocols and train and collaborate with students, postdoctoral fellows, technicians, and other laboratory personnel.
Culture cell lines and primary immune cells, including BMDC and BMDM; establish stable gene-expression or knockout cell lines using CRISPR.
Prepare single-cell suspensions from tissues.
Perform real-time PCR, western blotting, and RNAi.
Generate, isolate, and purify antibodies.
Perform ELISA using serum and supernatant.
Perform immunofluorescence staining using cells and tissues.
Maintain mouse colonies and perform genotyping with assistance from a technician.
Prepare, perform, and analyze samples using multicolor flow cytometry.
Troubleshoot experimental procedures and update them as needed.