Analytical Development Senior Research Associate

Vertex Inc.•Boston, MA

3d•$72,000 - $108,000•Onsite

About The Position

The Analytical Development Senior Research Associate independently performs complex experimental procedures designed through collaboration with their supervisor. Works collaboratively with the analytical team providing technical support to achieve program goals within established timelines and demonstrates excellent documentation skills. Independently performs troubleshooting as needed. Reports experimental findings and results to the team in an organized and clear manner. Authors method documents, analytical protocols and reports. Contributes to lab organization and efficient lab functioning. This individual will help advance transformative medicines treating the underlying cause of serious diseases by contributing to analytical activities for small molecule programs from preclinical through late stage development. Responsibilities include analytical support of process and formulation development activities, including purity and stability characterization of drug substance and drug product, as well as contributing scientifically to the resolution of broader drug development challenges in collaboration with other CMC functions. The ideal candidate will have knowledge of laboratory techniques commonly used in the analysis of pharmaceuticals such as HPLC, GC, and KF.

Requirements

Understanding of HPLC, KF, GC, and other techniques commonly used for pharmaceutical analysis
Proven technical proﬁciency and demonstrated skill in designing, executing and interpreting experiments
Uses own judgment to execute follow-up experiments, including troubleshooting
Demonstrated understanding of analysis and interpretation of complex experimental data with proﬁciency in problem solving and protocol reﬁnement
Effective communicator (written and verbal)
Emerging knowledge of regulatory guidance for analytical development
Ability to create and support a productive laboratory environment
Bachelor's degree (or equivalent degree) in Chemistry, Chemical Engineering, Pharmaceutical Chemistry, or related discipline and 4+ years of experience in analytical development program or other analytical support function, or Master's degree (or equivalent degree) in Chemistry, Chemical Engineering, Pharmaceutical Chemistry, or related discipline and 0-2 years of experience in analytical development program or other analytical support function
Knowledge and hands on experience with analytical techniques used for characterization and release assays (LC, GC, KF)

Responsibilities

Designs, executes, and interprets experiments within SOPs and regulations, with a high degree of reliability and independence
Collates and interprets data systematically, and compiles results into conclusions or recommendations for discussions with manager
Conducts experimental troubleshooting on a routine basis
Maintains accurate laboratory notebooks with inclusion of reference to sources of raw data
Prepares clearly defined protocols and written reports
Participates in the preparation of presentations and may present experimental results and conclusions at internal department or Project Team research meetings
Contributes collaboratively to team goals, providing technical support where needed