Analytical Chemist

Eli Lilly and CompanyIndianapolis, IN
Onsite

About The Position

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. Synthetic Molecule Design and Development have an exciting opportunity for an analytical chemist to join our development group. In this hands-on laboratory role (>70% bench work), you will develop analytical methods and characterize chemical processes to advance drug candidates from early development through manufacturing readiness. You will expand and apply your expertise in chromatographic method development and leverage complementary techniques (mass spectrometry, NMR) while partnering closely with synthetic chemists and process engineers to solve critical process development challenges. The ideal candidate brings practical chromatography experience, strong problem-solving skills, and the ability to translate analytical data into actionable insights for project teams.

Requirements

  • Bachelor or Master of Science degree in Analytical Chemistry, Biochemistry, Chemistry, or a related field.
  • Experience with chromatographic (LC, GC, IC) method development or validation in pharmaceutical, chemical, or regulated industry setting
  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Nice To Haves

  • Working knowledge of mass spectrometry (LC-MS, GC-MS) and NMR spectroscopy
  • Familiarity with chemical process development, synthetic organic chemistry, and rationales for establishing material specifications and testing plans.
  • Experience troubleshooting and maintaining analytical instrumentation.
  • Demonstration of scientific leadership and the ability to influence others.
  • Ability to balance multiple responsibilities, prioritize activities, and navigate ambiguity.

Responsibilities

  • Develop and optimize analytical methods to accurately measure purity, potency, and other critical quality attributes of small molecule drug substances and synthetic intermediates.
  • Select and implement appropriate analytical techniques (HPLC, GC, NMR, MS) to support chemical process development—independently generating data that elucidates reaction mechanisms, characterizes kinetic behavior, and identifies process-related impurities.
  • Assess stability of development materials under stressed conditions to evaluate potential degradation using chromatographic techniques.
  • Collaborate with synthetic chemists and process engineers to ensure analytical methods are suitable for guiding development activities and can be successfully transferred to GMP laboratories for routine testing and manufacturing support.
  • Perform laboratory activities with a strong emphasis on safety and technical rigor, while adhering to local policies and procedures.
  • Identify and apply new scientific concepts, exhibit strong problem-solving skills, and be self-motivated to contribute across multiple projects.
  • Demonstrate strong written and verbal communication skills to represent both the technical aspects and business-related implications of your work.

Benefits

  • company bonus (depending, in part, on company and individual performance)
  • company-sponsored 401(k)
  • pension
  • vacation benefits
  • medical, dental, vision and prescription drug benefits
  • flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
  • life insurance and death benefits
  • certain time off and leave of absence benefits
  • well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

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What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Education Level

Associate degree

Number of Employees

5,001-10,000 employees

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