Vice President, Project Management - RayzeBio

Bristol Myers Squibb • San Diego, CA

14h • $304,130 - $368,534 • Hybrid

About The Position

The Vice President of Project Management at RayzeBio serves as a strategic leader and thought partner, responsible for shaping and guiding a high‑performing project management organization that spans the full drug development continuum from discovery research through clinical development, manufacturing, regulatory approval, commercial launch, and lifecycle management. This role is pivotal in advancing RayzeBio’s pipeline by driving operational excellence, embedding project management discipline into decision‑making, and ensuring programs progress efficiently through critical milestones. The Vice President will coach and develop project management talent, foster a culture of collaboration and innovation, and align program execution with the company’s strategic goals while representing RayzeBio’s approach to project management excellence within the broader biotech industry.

Requirements

• Advanced degree in Life Sciences, Business Management, or related discipline preferred (e.g., PhD, PharmD, MS, MBA); PMP or equivalent project management certification is valued.
• 15+ years of progressive project management experience in the pharmaceutical or biotech industry, with at least 7 years in senior leadership roles driving complex, cross‑functional programs.
• Deep expertise in project and portfolio management across the drug development lifecycle, with demonstrated ability to integrate across multiple therapeutic areas and anticipate downstream implications from research through commercialization.
• Proven experience as a people leader with strong talent development skills, managing and mentoring teams, and building high‑performing matrix organizations.
• Demonstrated strength in partnering with executive leadership to assess critical business needs, influence portfolio decisions, and negotiate effectively in a matrixed environment.
• Track record of developing and executing strategic plans and initiatives that deliver measurable business outcomes, with the ability to resolve complex problems and manage challenging stakeholder dynamics.
• Strong communication skills with the ability to synthesize complex program data into clear, actionable insights and tailor messaging to diverse audiences, including senior executives and external partners.
• Proven track record of embedding AI, digital tools, and automation into portfolio operations to accelerate pipeline execution, strengthen project management discipline, and enable data‑driven decision making across the drug development lifecycle.

Responsibilities

• Provide strategic direction and leadership for the project management organization, ensuring alignment with RayzeBio’s objectives and pipeline priorities.
• Lead the project management for the NDA filing of our first asset (Player and coach required)
• Build industry‑leading asset and portfolio management capability across drug development to drive pipeline execution.
• Influence asset and portfolio decisions by identifying interdependencies and downstream implications across research, clinical, regulatory, medical, and commercialization.
• Guide decision‑making in the context of building portfolio value versus solely progression of individual assets.
• Lead, mentor, and develop a high‑performing project management organization across early and late drug development as a centralized capability.
• Drive portfolio excellence through standardized operating practices across therapeutic areas, fostering a culture of excellence and continuous improvement.
• Serve as process owner of asset progression across governance checkpoints from first‑in‑human through registration and submission.
• Mentor and guide talent development, including succession planning, performance management, and recognition.
• Enable cross‑TA talent development opportunities to build a pipeline of project management talent across RayzeBio and the broader BMS portfolio.
• Lead global program team objective management, integrated portfolio operations, portfolio health, risk management, and portfolio prioritization.
• Partner with therapeutic area leadership, Globa Program Leads (GPL’s), commercial, business insights, and technology functions to ensure portfolio alignment.
• Maintain oversight of portfolio health and proactively identify and escalate systemic issues requiring portfolio or enterprise‑level action.
• Design and lead initiatives to improve tools and processes for strategic planning and operations, specifically leveraging AI to simplify and eliminate low value human effort where possible and create competitive advantage via rate of program execution
• Drive planning excellence, including implementation of enterprise planning tools (e.g., e‑plan).
• Establish and monitor key performance indicators (KPIs) to track project progress.
• Use metrics to drive accountability and continuous improvement.
• Ensure all projects comply with regulatory requirements and industry standards.
• Maintain governance discipline across all stages of drug development.
• Oversee planning, execution, and delivery of early and late drug development programs.
• Ensure programs are completed on time, within scope, and within budget.
• Collaborate with internal and external stakeholders, including executive leadership in research, development, regulatory, safety, biometrics, data sciences, clinical, product development, commercial, and medical.
• Ensure alignment and success for jointly developed projects by coordinating closely with strategic alliance partners.
• Work closely with GPL’s (Global Program Leads) to facilitate appropriate decision making aligned with a biotech mindset
• Facilitate effective communication and collaboration among diverse teams to ensure alignment with project goals and timelines.
• Establish and lead forums and communities of practice to strengthen transparency, drive portfolio operations, and enable peer networking.
• Manage project management resources effectively, including budget, personnel, and technology.
• Optimize project efficiencies and delivery of business outcomes.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive