Vice President, Head of Global Translational Medicine & Research

Genmab•Princeton, TX

82d•Hybrid

About The Position

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees. Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so. Does this inspire you and feel like a fit? Then we would love to have you join us! Genmab is seeking a dynamic, inspirational and science-driven people leader to head our Global Translational Medicine & Research team. This is a unique opportunity to drive translational impact across a diversified pipeline of antibody formats, mechanisms of action, and indications. The Role As the Vice President, Head of Translational Medicine & Research, you will lead a global organization of 60+ scientists based in the US and the Netherlands. The team spans a broad spectrum of capabilities (including a translational lab in NL) and plays a pivotal role in shaping translational strategies from discovery through late-stage clinical development. The Global Head of Translational Medicine & Research (TM&R) will report to the Head of Translational & Quantitative Sciences. You will represent TM&R on the Translational & Quantitative Sciences Leadership Team and be responsible for: Providing scientific and strategic direction for the delivery of comprehensive pre-clinical and clinical translational data packages and derived insights, ensuring alignment with organizational goals and regulatory standards Advancing biomarker strategies and applying insights to clinical development. Driving innovation, scientific excellence, and team development. Acting as an ambassador of Genmab science in both internal and external forums. This is an exciting opportunity to lead a passionate, high profile, high-impact translational team, and work in a highly dynamic and collaborative setting. We have a hybrid model that requires being onsite 60% of the time in Princeton, NJ or Utrecht, NL.

Requirements

PhD or MD/PhD in a relevant scientific field (e.g. Immunology, Oncology, Molecular Biology).
15-20+ years of drug development experience in biotech/pharma, with demonstrated leadership in translational science or biomarker strategy
Strong track record of influencing drug development decisions from preclinical to late-stage programs
Experience leading large, multidisciplinary teams and fostering global collaboration
Exceptional communication and stakeholder management skills
Commitment to scientific excellence, strong work ethics, and a passion for translational studies to serve as an inspiration to the team

Responsibilities

Lead global TS TM&R efforts supporting translational strategies, planning, data generation, and insight delivery across all stages of development
Oversee the development and implementation of biological mechanisms into actionable hypotheses to guide translational strategies that inform trial design, dose optimization, patient selection/stratification, combinations, efficacy monitoring and drive data-driven decision-making
Conduct recurrent reviews of translational strategies across the portfolio to refine strategic and tactical approaches based on emerging data, medical need, and changes in the treatment landscape.
Support data contextualization for regulatory submissions, publications, and scientific communications
Review and approve integration of translational content into regulatory applications including INDs, BLAs, Clinical Study Protocols and Reports, and other regulatory documents (Technical Reports, Regulatory submissions and responses, etc.)
Represent TM&R across internal governance bodies and external collaborations
Champion the application of novel technologies to inform decision-making and enable compound differentiation
Partner with cross-functional teams to implement AI/ML models for translational insight generation to optimize and accelerate asset development
Contribute to building foundational knowledge across formats, targets, and safety profiles
Actively engage with key opinion leaders, technology companies, foundations to advance translational initiatives
Oversee scientific writing, ensuring high-quality contributions to patents, regulatory documentation, publications, and external presentations across the portfolio
Present Genmab’s translational science at global conferences, expert panels, and in collaboration with academic institutions
Participate in patient advocacy groups and support initiatives to advance patient engagement
Strategically plan workforce capabilities and enable a high-performing global team
Promote scientific and leadership development through targeted training and mentoring
Drive employee engagement and well-being, leveraging insights from engagement surveys and continuous feedback
Foster a culture that emphasizes scientific rigor, productivity, and collaboration
Create a supportive and inclusive workspace that encourages diverse ideas and perspectives

Benefits

401(k) Plan: 100% match on the first 6% of contributions
Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

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