Vice President, Clinical Science and Operations

Geron Corporation

8h•$325,000 - $365,000•Remote

About The Position

The Vice President of Clinical Science and Operations is a senior leadership role responsible for the oversight, execution, and strategic direction of clinical development programs across all phases, including post-marketing activities. The Vice President ensures milestones are achieved and ensures that Clinical Science and Clinical Operations strategies align with corporate goals, regulatory requirements, and industry best practices to advance the Company’s product pipeline, support commercialization efforts, and optimize post-marketing data and evidence generation. The Vice President is accountable for delivering high-quality clinical programs across all phases (I–IV), including post-marketing studies, ensuring alignment with regulatory, commercial, and organizational goals. The Vice President plays a critical role in guiding cross-functional teams, optimizing trial design and execution, and mentoring talent within the clinical organization. The Vice President is a critical member of the early- and late-stage Product Development Team (PDT) and Research and Development Leadership Team (RDLT) and works to drive proactive identification and resolution of clinical project issues. This position is remote with a corporate headquarters in Foster City, CA and Parsippany, NJ. The Vice President will report to the Executive Vice President, R&D and Chief Medical Officer.

Requirements

In-depth knowledge of clinical drug development, trial execution, study management, and monitoring procedures
Strong understanding of IND enabling activities and studies
Strong understanding of trial design, clinical methodology, and study protocols across phases and indications
Expertise in post-marketing studies, real-world evidence generation, and lifecycle management
Well-versed in GCP, ICH guidelines, and global regulatory requirements (FDA, EMA, etc.)
Strong analytical skills with the ability to translate complex data into actionable insights
Strategic mindset with proven ability to balance long-term planning and day-to-day execution
Financial acumen with ability to assess and manage budget scope changes
Proven leadership and team-building skills with a focus on results and accountability
Ability to lead and collaborate across cross-functional teams, including CROs and external vendors
Ability to motivate teams to meet deadlines and project goals with minimal oversight
Excellent verbal and written communication skills
Polished presenter with the ability to engage internal and external stakeholders effectively
Strong interpersonal skills with a professional, service-oriented mindset
Highly organized, self-motivated, and capable of independent decision-making
Strong ability to resolve project issues and prioritize competing demands
Committed to continuous improvement and process optimization
Advanced degree (MD, PhD or PharmD preferred) in medicine, pharmacology, biology, or a related field strongly preferred; Bachelor’s degree in a scientific discipline plus extensive clinical experience will also be considered
Minimum of 15 years of experience in clinical development, including leadership roles
Proven track record of success in leading clinical programs through regulatory approval, commercialization, and post-marketing phases
Experience building and leading cross-functional teams
Previous experience with pre-clinical and Phase I - IV studies
Previous experience managing CROs/vendors

Responsibilities

Lead and integrate the scientific and operational strategies for clinical development programs, spanning early development and Phases I–IV and post-marketing studies, to support regulatory submissions, commercialization, and lifecycle management
Collaborate with executive leadership and cross-functional partners to align clinical development plans with corporate objectives and commercial priorities as part of RDLT
Provide guidance to the Chief Medical Officer, Head of R&D, and senior leaders on clinical trial design, data interpretation, risk management, and scientific rigor
Direct the development and oversight of clinical protocols, study designs, and scientific plans as a member of the early- and late-stage PDTs
Oversee planning, initiation, and execution of clinical trials, ensuring delivery on time and with high quality
Oversee feasibility assessments and select trial geographies to ensure strategic fit and operational efficiency
Drive site/investigator selection, engagement, and relationship management to optimize enrollment and site performance
Oversee contract research organization (CRO) and vendor management, ensuring compliance, performance, and issue resolution
Manage clinical program budgets, track spending, and align resources with portfolio priorities
Oversee and support post-marketing trials and real-world evidence generation initiatives on safety, efficacy, and market value
Support collection, analysis, and reporting of clinical and post-marketing data to ensure accurate safety monitoring and continuous product profile optimization
Engage and collaborate with key opinion leaders, healthcare professionals, vendors, and CROs to enhance study execution, scientific validity, and product adoption
Lead, mentor, and develop high-performing Clinical Science and Clinical Operations teams, fostering a culture of innovation, accountability, and continuous professional growth
Ensure Clinical Science and Clinical Operations deliverables meet timelines, budget, quality, and compliance standards
Ensure clinical trials comply with ICH-GCP, global regulatory guidelines, and internal SOPs
Drive proactive identification and resolution of clinical and operational issues and lead process improvement initiatives
Represent the Clinical Science and Clinical Operations departments in internal leadership forums, external presentations, and cross-functional governance bodies
Collaborate on the preparation of regulatory submissions, including post-marketing commitments, safety updates, and payer evidence packages as part of RDLT
Lead and contribute to process improvement initiatives, development of department SOPs, and clinical development plans

Benefits

All regular-status, full-time employees of Geron are eligible to participate in the Company’s comprehensive benefit program, pursuant to plan terms and conditions.
Plan choices include medical, dental, vision, life insurance, flexible spending accounts, disability insurance, supplemental health insurance, a 401(k) retirement savings plan, and an employee stock purchase plan.
Geron also provides regular-status, full-time employees with a generous time off program that includes the eligibility to accrue 160 hours of vacation during each full year of employment, 64 hours of sick leave, 9 standard paid holiday days off, and paid leave for certain life events.
Geron recognizes that its employees work in many different states and therefore may be affected by different laws.
It is Geron’s intention to comply with all applicable federal, state, and local laws that apply to the Company’s employees.

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