Staff Accountant

Prime Medicine • Cambridge, MA

7d • Hybrid

About The Position

The Staff Accountant will play a key role in the accounting and financial activities for Prime Medicine. In this crucial role, the Staff Accountant will have exposure to a wide range of business and operational initiatives, accounting and financial reporting activities and ad hoc projects.
This role is focused on monthly and quarterly close financial procedures and supports the Procure-to-Pay functions. The candidate will join an evolving finance and accounting team recognized as valued business partners. This position offers exposure to many levels of the organization, providing outstanding opportunities to influence the direction of the business and to grow your career.
Position will report directly to Associate Director of Procurement.

Requirements

• Bachelor’s degree in finance or accounting (preferred), with 2-3 years of progressive accounting experience with at least 2 years in public accounting or a high-growth tech/life sciences company
• Strong understanding of U.S. GAAP and willingness to deepen technical accounting knowledge
• Proficiency in MS Office (especially Excel) and experience with accounting/ERP software
• Demonstrated analytical skills to solve complex problems and address a variety of variables in situations with limited standardization
• Strong organizational skills to effectively balance priorities, handle workload, and complete projects on time
• Highly organized and diligent, with time management abilities
• Strong interpersonal skills for effectively communicating with internal & external stakeholders of all levels.
• Ability to work independently across multiple financial systems and troubleshoot/resolve issues as needed.
• Self-motivated and capable of working independently
• Hybrid work position with some in-person attendance required (Cambridge, MA)

Responsibilities

• Execute month-end, quarter-end, and year-end close activities in a timely and accurate manner, including preparation and posting of journal entries, account reconciliations, roll forwards and variance analyses
• Provide internal customer service support for the Procure-to-Pay (P2P) processes and day-to-day activities, ensuring users are properly trained and transactions are recorded accurately
• Maintain Vendor Master File and act as the primary contact for vendor inquiries regarding payment status and statement reconciliation
• Lead efforts around accounts payable efficiencies, including driving automation and other process enhancements
• Manage weekly cash disbursement processes, coordinate payment approvals and payment timing
• Oversee and manage Concur for employee expense reports from review to reimbursement, ensuring compliance with company policies
• Manage fixed assets and depreciation ensuring compliance with accounting standards and company policies
• Support external and internal audits by preparing schedules, reconciliations, and documentation
• Ensure business transactions continue to be in accordance with generally accepted accounting principles, policies, and SOX controls
• Assist with special projects and ad-hoc analysis across accounting functions as assigned

Benefits

• Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Number of Employees: 101-250 employees