Sr. Director, Global IT Infrastructure & Operations

Repligen Corporation • Waltham, MA

5d

About The Position

Repligen is seeking a hands-on, strategic Sr. Director, Global IT Infrastructure & Operations to lead the design, implementation, and ongoing optimization of our global technology infrastructure, end-user services, and site support. This role partners closely with business and IT stakeholders to build an infrastructure & end-user services roadmap aligned to business strategy, while overseeing internal teams, MSPs, and vendors to ensure high-quality, secure, and reliable services. You will lead and develop a high-performing team, drive continuous improvement, and ensure our infrastructure and end-user computing needs meet the needs of a fast-growing, globally distributed Life Sciences organization .

Requirements

• 15 years of progressively responsible experience in IT Infrastructure & Operations leadership.
• Broad technical background covering infrastructure, network, storage, cloud, data center, and virtualization technologies.
• Deep technical knowledge in network and server security; FortiOS and Nutanix highly desirable.
• Strong understanding of ITIL processes (incident, problem, change management).
• Demonstrated success delivering high-quality customer service, including at the executive level.
• Expert knowledge of: LAN/WAN, DNS, Active Directory Data center operations Firewalls/VPNs Server setup/configuration/administration Virtualization technologies Automation and IaC tools and implementations
• Experience managing GxP and SOX-compliant systems (Life Sciences preferred).
• Strong vendor management and contract negotiation experience.
• Proven ability to build, lead, and develop high-performing technical teams.
• Strong critical thinking, problem-solving, and communication skills.

Responsibilities

• Strategic Leadership & Architecture Develop and maintain the global IT/OT infrastructure architecture aligned to business goals and Life Sciences regulatory requirements.
• Evaluate people, processes, and technologies to ensure an optimal global infrastructure strategy.
• Plan and lead infrastructure and cloud design, upgrades, scalability, and modernization efforts.
• Plan and lead daily IT operations using ITSM practices, collaborating on cybersecurity and compliance, and leading a global team.
• Technical & Operational Execution Provide Tier 3+ technical leadership for incident and problem resolution.
• Oversee network, cloud, server, data center, storage, telecommunications, industrial control systems, and mobile device management environments.
• Drive daily IT operations using best-practice ITSM frameworks (ITIL).
• Ensure robust incident, problem, and change management processes are in place to meet stringent Service Level Agreements (SLAs) for critical business systems.
• Ensure continuous monitoring, performance optimization, and documentation standards.
• Drive GxP-compliant infrastructure planning, capacity management, and validation practices.
• Vendor, MSP & Budget Management Manage MSPs, vendors, and partners to ensure SLA-driven service delivery.
• Lead vendor contract negotiations and performance governance.
• Manage infrastructure and operations budgets and investment business cases to support new technologies and lifecycle management.
• Ensure vendor and financial management, developing disaster recovery plans, and collaborating with other teams.
• Security, Risk & Compliance Assess infrastructure risks and implement technologies/processes to mitigate them.
• Ensure compliance with cybersecurity requirements, SOX/GxP standards, and ITIL processes.
• Maintain reliable, repeatable processes for change, patching, provisioning, and validation.
• Innovation & Continuous Improvement Proven track record of successfully modernizing legacy IT environments, implementing cloud-first strategies, and driving automation and Infrastructure-as-Code principles.
• Research and recommend new technologies that enable innovation, efficiency, or cost optimization.
• Lead infrastructure & operations projects, including new capabilities, site expansions, and facility moves.
• Implement enhancements that improve reliability, performance, and user experience.

Benefits

• We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts.
• All compensation and benefits information will be confirmed in writing at the time of offer.

What This Job Offers

• Job Type: Full-time
• Career Level: Manager
• Education Level: No Education Listed
• Number of Employees: 1,001-5,000 employees