Senior Scientist, Protein Analytics

Bristol Myers Squibb

1d•Onsite

About The Position

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology, and cardiovascular disease – and with one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contributes to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Position Summary We are seeking a highly skilled Senior Scientist to join our Protein Analytics team. This role is primarily bench-focused, supporting the analytical characterization of large molecule therapeutics including monoclonal antibodies, antibody-drug conjugates (ADCs), multispecifics, and other biotherapeutics, while also managing a contractor to ensure smooth execution of laboratory activities. The successful candidate will contribute to a dynamic and collaborative group responsible for high-resolution and high-throughput analytical assays to evaluate the quality, structure, and function of drug candidates. Based at the BMS Discovery Biotherapeutics Cambridge Crossing, MA site, you will represent the analytics function on multiple projects and collaborate closely with project teams to deliver high-quality data that informs drug discovery decisions.

Requirements

Ph.D. in Chemistry, Biochemistry, Analytical Sciences, or related discipline with 3–5 years of relevant industry experience, OR M.S. with 8–10 years of experience in protein analytics or biopharmaceutical characterization.
Strong understanding of protein structure, post-translational modifications, and analytical method development.
Demonstrated ability to interpret complex MS data and communicate results effectively to multidisciplinary teams.
Excellent organizational and technical skills, with the ability to manage multiple priorities in a fast-paced environment.
Enthusiasm, willingness to learn, and strong work ethic.

Nice To Haves

Hands-on experience with advanced mass spectrometry techniques such as peptide mapping, glycan profiling, drug-to-antibody ratio (DAR) determination, and native MS is highly desirable
Familiarity with automation, electronic lab notebooks, and LIMS systems.

Responsibilities

Perform detailed analytical characterization of large molecules using techniques such as LC-MS, LC-MS/MS, SEC-MALS, HIC, CE-SDS and other state-of-the-art methodologies.
Develop, optimize, and execute analytical methods for assessing purity, identity, heterogeneity, and post-translational modifications of biotherapeutics
Support high-throughput analytical workflows for early-stage lead selection and candidate profiling.
Maintain and troubleshoot analytical instrumentation
Clearly document experiments, analyze data, and present results and conclusions to project teams and stakeholders.
Collaborate with multidisciplinary teams to support project goals and timelines
Manage a contractor, including task assignment, prioritization, and ensuring compliance with laboratory standards and safety practices.

Benefits

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

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