Senior Scientist - Medicinal Chemistry, Oncology Targeted Discovery
About The Position
As a Senior Scientist, you will actively contribute to programs in the Oncology Targeted Discovery (OTD) chemistry group. This role is part of our strategy to deliver highly specific state-of-the-art therapeutics including, but not limited to, small molecules, peptides and antibody drug conjugates to treat cancer. The successful candidate will deploy expert-level synthetic organic chemistry skills in designing and building complex molecules, both small and non-small, in the laboratory to drive innovation. Working together with various disciplines, you will have the opportunity to acquire world-class medicinal chemistry skills and contribute to a thriving portfolio of future cancer medicines covering a wide range of modalities. There will also be a chance to support development and adoption of machine-learning/AI tools and emerging technologies. This job posting is for our group at the Waltham, MA location (with expectation to move to our new Kendall Square, Cambridge, MA site in Q3 2026).
Requirements
- Doctoral degree (Ph.D.) or equivalent focused in synthetic organic or medicinal chemistry with 0+ years of experience in the academia, biotech and/or pharmaceutical industry
- Strong record of peer-reviewed publications and of problem solving to drive scientific innovation
- Expert-level synthetic chemist with intuition for chemical reactivity and awareness of latest scientific literature
- Strong work ethic and adherence to safe practices in the laboratory
Nice To Haves
- Prior exposure to basic AI/ML tools, computational design and emerging modalities such as bioconjugation is preferred
Responsibilities
- Design and execute multi-step modular routes compatible for rapid access to small molecule targets (strong organic synthesis background is required)
- Routinely separate, purify and analyze chemical matter, both small and non-small, using validated techniques and protocols
- Employ quantitative and hypothesis-driven approaches to experimentation, including ability to interpret SAR
- Learn to conduct research by deploying machine-learning/AI tools in seamlessly interactive manner
- Demonstrate a collaborative team player mindset and enthusiasm for multidisciplinary research in a fast-paced environment across various internal/external partners
- Participate in writing and submission of patent applications, peer-reviewed articles, and abstracts for scientific conferences
- Ensure that appropriate safety, health & environment (SHE) practices are followed
Benefits
- qualified retirement programs
- paid time off (i.e., vacation, holiday, and leaves)
- health, dental, and vision coverage
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
