Senior Research Associate, Single Cell Technology

NewLimitSouth San Francisco, CA
2d$90,000 - $110,000

About The Position

NewLimit is a biotechnology company working to radically extend human healthspan. We are developing medicines to treat age-related diseases by reprogramming the epigenome—a novel therapeutic mechanism designed to restore regenerative potential in aged and diseased cells. By leveraging functional genomics, pooled perturbation screening, and machine learning, we unravel the biology of epigenetic aging through experiments of unprecedented scale. Position NewLimit is seeking a Senior Research Associate with experience in molecular biology and automation to join our Single Cell Technology group. Single cell genomics is one of the key enabling technologies for our research programs, allowing us to measure the transcriptional and epigenetic state of millions of cells to guide therapeutic discovery.

Requirements

  • Bachelor’s degree in cell biology, molecular biology, engineering or a related natural science field
  • 2+ years of work experience in molecular biology laboratory techniques and their automation (academic or industry)
  • Experience with liquid handling systems for automating molecular biology, NGS and/or cell culture protocols
  • Experience with NGS protocols & workflows (e.g., nucleic acid extraction, PCR, library construction and QC) and/or sample preparation for genomic applications including tissue isolation, dissociation, and cell culture

Nice To Haves

  • Proficiency in programming, optimizing, and troubleshooting Hamilton liquid handlers using VENUS software
  • Experience with single cell genomics methods
  • Experience with flow cytometry sorting for single-cell preparations
  • Experience with molecular cloning

Responsibilities

  • Collaborate with our Epigenetic Editing team to perform large-scale, single cell perturbation experiments
  • Perform state-of-the-art single cell profiling experiments to map epigenetic features of aging
  • Implement, operate, and maintain laboratory automation protocols for molecular biology and next-generation sequencing (NGS) experiments
  • Contribute to experimental sample preparation (e.g., animal dissections, tissue harvesting, primary cell culture) and execution of molecular and cellular assays

Benefits

  • Comprehensive Health, Dental, and Vision insurance
  • 401(k) plan with company match
  • Paid parental leave
  • Industry-leading PTO: 20 days per year plus holidays
  • On-site meals and snacks
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